Synthetic organic chemistry has developed in a fascinating way over the past decades.
Several highly selective procedures have been developed which allow the preparation of …

Natural and synthetic cyclopropanes bearing simple functionalities are endowed with a
large spectrum of biological properties ranging from enzyme inhibitions to insecticidal …

A new, interdisciplinary research area has emerged known as bioorganometallic chemistry.
It focuses on the introduction of organometallic fragments into biomolecules (see, for …

Peptide and protein biological activities depend on their three dimensionals structures in the
free state and when interacting with their receptors/acceptors. The backbone conformations …

None of the naturally occurring amino acids containing a cyclopropyl group is proteinogenic,
but most of them bring about some interesting and important biological activity. This also …

Alkylation of stabilized carbanions is the most fundamental carbon±carbon bond-forming
reaction in organic chemistry. 1 Recent NMR and X-ray analyses, stimulated by the central …

Conformationally constrained amino acids (AAs) have been the focus of both synthetic and
medicinal chemistry, particularly as they apply to the design of novel peptides. 1 Rigidified …

Ogawa et al., CA113: 111406, 1990.* Gaucher, Et Al:“Palladium (0) Catalyzed Tandem
Alkyla tion and SN'Cyclization of 1, 4-Dichlorobut-2-ene by the N-(Diphenylmethylene) …

US6323180B1 - Hepatitis C inhibitor tri-peptides - Google Patents US6323180B1 -
Hepatitis C inhibitor tri-peptides - Google Patents Hepatitis C inhibitor tri-peptides …

Chen, Et Al;“Kinetic resolution of esters of amino acids in t—butanol containing 5% Water
catalyzed by stable industrial alkaline protease”, Chirality, vol. 6, 1994, p. 572—576. Llinas …