Improving powder performances of natural extracted lutein with spherulitic growth control

W Guo, L Wang, P Shi, Y Wang, Y Liu, L Tong, T Li… - Powder Technology, 2022 - Elsevier
Lutein tends to form tiny lamellar crystals which result in poor powder performances in
uniformity of particle size and flowability. Spherulitic growth technology is developed to …

Spherulitic growth strategy: Improving the stability of metastable form and particle performances of m-aminobenzoic acid

C Liu, Y Xiao, Y Xiao, Y Jing, Y Bao - Powder Technology, 2023 - Elsevier
In this study, we investigated the morphology modification of m-aminobenzoic acid (m-ABA)
needle-like crystals using a spherulitic growth strategy to enhance their particle …

Spherulitic growth strategy for agitation-induced formation of spherical amoxicillin sodium products

P Cui, W Yang, L Jia, L Zhou, M Zhang… - Industrial & …, 2022 - ACS Publications
In industrial crystallization, spherical crystals have gained increasing interest due to their
excellent physicochemical properties, such as high bulk density, flowability, stability, etc …

Crystallization of lithium carbonate from aqueous solution: new insights into crystal agglomeration

W Yang, L Zhou, J Dai, L Zhou, M Zhang… - Industrial & …, 2019 - ACS Publications
In this work, crystal agglomeration of lithium carbonate has been studied from a new point of
view. During an in situ crystallization experiment of lithium carbonate, a continuous structural …

Transformation between two types of spherulitic growth: tuning the morphology of spherulitic nitroguanidine in a gelatin solution

J Yang, Y Cui, M Chen, Y Wang, S Xu… - Industrial & …, 2020 - ACS Publications
Spherulitic growth, categorized as central multidirectional growth and unidirectional growth
via small-angle branching, has increasingly been explored as a method to improve the …

Growth mechanism of the spherulitic propylthiouracil–kaempferol cocrystal: new perspectives into surface nucleation

Y Xiao, W Yang, L Zhou, H Hao, Y Bao, Q Yin, C Xie - CrystEngComm, 2021 - pubs.rsc.org
As an emerging technology that can simultaneously improve the powder performance and
bioavailability of drugs, spherulitic cocrystallization has increasingly shown its unique …

Improving Powder Performances of d-Ribose through Spherulitic Growth

D Wang, X Zhou, Y Liu, M Chen, D Han… - Industrial & …, 2024 - ACS Publications
With the rise of research on functional sugar, we found that preparing crystalline powders
into spherical crystals will significantly improve quality, stability, appearance, and texture. In …

[HTML][HTML] Supersaturation-driven self-assembly formation of ceftriaxone sodium spherulites: From amorphous form to spherulites

S Liang, Y Niu, X Hu, W Xiao, X Ruan, G He, X Jiang - Particuology, 2024 - Elsevier
Drug particles with spherical morphology possess amazing advantages in terms of particle
flowability, mechanical properties, drug solubility, and bioavailability. The growth …

Determination and analysis of solid–liquid equilibria for ternary systems Na2SO4–H2O2–H2O and Na2CO3–H2O2–H2O at 5 °C

Y Liu - Journal of Chemical Research, 2024 - journals.sagepub.com
To develop a better process for synthesizing sodium percarbonate and getting separation of
the sodium salt, the equilibrium of the ternary system Na2SO4–H2O2–H2O and Na2CO3 …

Application of functionalized magnetic silica nanoparticles for selective induction of three coumarin metastable polymorphs

Y Chen, X Huang, S Ding, Y Feng, N Wang… - Chinese Journal of …, 2022 - Elsevier
The precise control of active pharmaceutical ingredient (API) crystal nucleation and
polymorphism is a key consideration in pharmaceutical manufacturing. In this study, tunable …