Abstract Exportin 1 (XPO1), also known as chromosome region maintenance protein 1,
plays a crucial role in maintaining cellular homeostasis via the regulated export of a range of …

Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Survivin is a member of the inhibitor of apoptosis (IAP) gene family that has attracted
attention from several viewpoints of basic and translational research. Its cell cycle-regulated …

The inhibitor of apoptosis proteins (IAPs) are a family of antiapoptotic proteins that bind and
inhibit caspases 3, 7, and/or 9, but not caspase 8. Growing evidence also indicates that IAPs …

Survivin, an inhibitor of apoptosis protein, is highly expressed in most cancers and
associated with chemotherapy resistance, increased tumor recurrence, and shorter patient …

Survivin is a 16.5 kDa protein overexpressed in almost all malignancies but rarely detected
in normal differentiated adult tissues. Functionally, survivin has been shown to inhibit …

Apoptosis is a crucial biological process that prevents uncontrolled cell proliferation and
eliminates harmful cells. Resistance to apoptotic stimuli is a hallmark feature of various …

Survivin, a novel member of inhibitor of apoptosis (IAP) protein family, is aberrantly
expressed in cancer but undetectable in normal, differentiated adult tissues. Current studies …

Growing evidence suggests that survivin expression in cancer cell nuclei may represent an
important prognostic marker to predict disease outcome for cancer patients. Current reports …

Squamous cell carcinoma (SCC) is the most common cancer worldwide. The treatment of
locally advanced disease generally requires various combinations of radiotherapy, surgery …