Targeting the Warburg Effect in Cancer: Where Do We Stand?

I Barba, L Carrillo-Bosch, J Seoane - International Journal of Molecular …, 2024 - mdpi.com
The Warburg effect, characterized by the preferential conversion of glucose to lactate even
in the presence of oxygen and functional mitochondria, is a prominent metabolic hallmark of …

[HTML][HTML] Quo Vadis Hyperpolarized 13C MRI?

P Wodtke, M Grashei, F Schilling - Zeitschrift für Medizinische Physik, 2023 - Elsevier
Over the last two decades, hyperpolarized 13 C MRI has gained significance in both
preclinical and clinical studies, hereby relying on technologies like PHIP-SAH …

[HTML][HTML] Artificial Intelligence and Deep Learning for Screening and Risk Assessment of Cancers

M Farrokhi, SJ Khouzani, M Farrokhi, H Jalayeri… - Kindle, 2024 - preferpub.org
Abstract Artificial Intelligence (AI) and Deep Learning have emerged as revolutionary tools
in the domain of cancer screening and risk assessment. Leveraging vast amounts of data …

MRI Application and Challenges of Hyperpolarized Carbon-13 Pyruvate in Translational and Clinical Cardiovascular Studies: A Literature Review

F Frijia, A Flori, G Giovannetti, A Barison, L Menichetti… - Diagnostics, 2024 - mdpi.com
Cardiovascular disease shows, or may even be caused by, changes in metabolism.
Hyperpolarized magnetic resonance spectroscopy and imaging is a technique that could …

In vivo molecular imaging of breast cancer metabolic heterogeneity using [1-13C] pyruvate-d3 hyperpolarized by reversible exchange with parahydrogen

S Petersen, L Nagel, P Groß, R Willing, L Heß… - 2024 - chemrxiv.org
Metabolic MRI using hyperpolarized (HP)[1-13C] pyruvate is promising for diagnostic
medicine, allowing the study of cancer metabolism and early detection of therapy response …

Integrating molecular pathway with genome-wide association data for causality identification in breast cancer

YS Li, HC Jiang - Discover Oncology, 2024 - Springer
Objective The study purpose was to explore the causal association between pyruvate
metabolism and breast cancer (BC), as well as the molecular role of key metabolic genes, by …

[PDF][PDF] MRI 特征辅助分类乳腺癌分子亚型的临床研究

F GUO, X HOU, H ZHANG, Z SONG - CHINESE JOURNAL OF …, 2024 - diagnoschina.com
目的应用磁共振(MRI) 图像中提取的特征和机器学习方法来帮助区分乳腺癌分子亚型,
以期为临床诊治提供参考. 方法回顾性分析我院于2021 年10 月-2023 年10 月间确诊的178 …

Mechanism of the Warburg effect and its role in breast cancer immunotherapy

ES Saheed, RF Aromolaran, AD Atoyebi, FC Adeleke… - Discover …, 2024 - Springer
Breast cancer remains a significant global health concern affecting millions of women
annually. An essential aspect of this disease is the Warburg effect, which is a metabolic …