Nonenzymatic metabolic reactions and life's origins

KB Muchowska, SJ Varma, J Moran - Chemical Reviews, 2020 - ACS Publications
Prebiotic chemistry aims to explain how the biochemistry of life as we know it came to be.
Most efforts in this area have focused on provisioning compounds of importance to life by …

[HTML][HTML] Origins of building blocks of life: A review

N Kitadai, S Maruyama - Geoscience Frontiers, 2018 - Elsevier
How and where did life on Earth originate? To date, various environments have been
proposed as plausible sites for the origin of life. However, discussions have focused on a …

The physiology and habitat of the last universal common ancestor

MC Weiss, FL Sousa, N Mrnjavac, S Neukirchen… - Nature …, 2016 - nature.com
The concept of a last universal common ancestor of all cells (LUCA, or the progenote) is
central to the study of early evolution and life's origin, yet information about how and where …

Prebiotic systems chemistry: new perspectives for the origins of life

K Ruiz-Mirazo, C Briones, A de la Escosura - Chemical reviews, 2014 - ACS Publications
The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

Protocells and RNA self-replication

GF Joyce, JW Szostak - Cold Spring Harbor Perspectives …, 2018 - cshperspectives.cshlp.org
The general notion of an “RNA world” is that, in the early development of life on the Earth,
genetic continuity was assured by the replication of RNA, and RNA molecules were the chief …

[HTML][HTML] Artificial cells: from basic science to applications

C Xu, S Hu, X Chen - Materials Today, 2016 - Elsevier
Artificial cells have attracted much attention as substitutes for natural cells. There are many
different forms of artificial cells with many different definitions. They can be integral biological …

Engineering functional polymer capsules toward smart nanoreactors

J Gaitzsch, X Huang, B Voit - Chemical reviews, 2016 - ACS Publications
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …

Versatile phospholipid assemblies for functional synthetic cells and artificial tissues

X Wang, H Du, Z Wang, W Mu, X Han - Advanced materials, 2021 - Wiley Online Library
The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

Biological autonomy

A Moreno, M Mossio - A philo, 2015 - Springer
If we were to point out in a few words what characterises the phenomenon of life, we would
probably mention the amazing plasticity and robustness of living systems, the innumerable …

Self-reproducing catalytic micelles as nanoscopic protocell precursors

A Kahana, D Lancet - Nature Reviews Chemistry, 2021 - nature.com
Protocells at life's origin are often conceived as bilayer-enclosed precursors of life, whose
self-reproduction rests on the early advent of replicating catalytic biopolymers. This …