Heart failure (HF) is characterized by a progressive decline in cardiac function and
represents one of the largest health burdens worldwide. Clinically, 2 major types of HF are …

With advances in sequencing, individuals with clonal hematopoiesis of indeterminate
potential (CHIP) are increasingly being identified, making it essential to understand its …

Abstract Background and Aims Both clonal haematopoiesis of indeterminate potential
(CHIP) and atrial fibrillation (AF) are age-related conditions. This study investigated the …

Increased left atrial volume and decreased left atrial function have long been associated
with atrial fibrillation. The availability of large-scale cardiac magnetic resonance imaging …

Importance Clonal hematopoiesis of indeterminate potential (CHIP), the age-related clonal
expansion of hematopoietic stem cells with leukemogenic acquired genetic variants, is …

Unlike other forms of somatic mosaicism such as cancer, CH is a premalignant state that
becomes a nearubiquitous phenomenon with advanced age. Because this condition is not …

age-associated condition whereby a proportion of mature blood cells originate from a single
dominant hematopoietic stem cell (HSC) clone. This phenomenon can arise from a somatic …

Two studies now report that TET2-driven clonal haematopoiesis of indeterminate potential
(CHIP) is associated with poor prognosis in patients with heart failure (HF) and preserved …

Zusammenfassung Herz-Kreislauf-Erkrankungen zählen zu den führenden Todesursachen
weltweit, wobei bekannte modifizierbare Risikofaktoren wie Rauchen, Übergewicht …