Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

E Martino, G Casamassima, S Castiglione… - Bioorganic & medicinal …, 2018 - Elsevier
Cancer still represents a “nightmare” worldwide, causing annually millions of victims.
Several antiproliferative molecules are currently used as drugs market and offer a …

A review on mechanistic insight of plant derived anticancer bioactive phytocompounds and their structure activity relationship

K Mazumder, A Aktar, P Roy, B Biswas, ME Hossain… - Molecules, 2022 - mdpi.com
Cancer is a disorder that rigorously affects the human population worldwide. There is a
steady demand for new remedies to both treat and prevent this life-threatening sickness due …

Differential scanning calorimetry (DSC): a tool to study the thermal behavior of lipid bilayers and liposomal stability

C Demetzos - Journal of liposome research, 2008 - Taylor & Francis
Thermodynamical techniques are applied for determining the thermal stress of medicinal
compounds of the excipients as well as their interactions during the formulation process. The …

Drug delivery systems and combination therapy by using vinca alkaloids

CT Lee, YW Huang, CH Yang… - Current topics in …, 2015 - ingentaconnect.com
Developing new methods for chemotherapy drug delivery has become a topic of great
concern. Vinca alkaloids are among the most widely used chemotherapy reagents for tumor …

Insights into molecular mechanism of action of citrus flavonoids hesperidin and naringin on lipid bilayers using spectroscopic, calorimetric, microscopic and theoretical …

C Altunayar-Unsalan, O Unsalan… - Journal of Molecular …, 2022 - Elsevier
Hesperidin and naringin are predominant flavonoids in citrus fruits and exert various
biological activities. However, mechanism of these activities has not been completely …

Optimization and characterization of thymoquinone-loaded liposomes with enhanced topical anti-inflammatory activity

M Mostafa, E Alaaeldin, UF Aly, HA Sarhan - Aaps Pharmscitech, 2018 - Springer
Thymoquinone, the major constituent of Nigella sativa oil has been found to have a
promising topical anti-inflammatory activity; however, exaggerated heat and photo-sensitivity …

[图书][B] Liposomes, lipid bilayers and model membranes: from basic research to application

G Pabst, N Kučerka, MP Nieh, J Katsaras - 2014 - books.google.com
As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …

Development of natural bioactive alkaloids: anticancer perspective

A Patel, R Vanecha, J Patel, D Patel… - Mini Reviews in …, 2022 - ingentaconnect.com
Cancer is a frightful disease that still poses a'nightmare'worldwide, causing millions of
casualties annually imposing one of the human race's greatest health-care challenges that …

Tetra-and penta-cyclic triterpenes interaction with lipid bilayer membrane: a structural comparative study

R Abboud, C Charcosset, H Greige-Gerges - The Journal of Membrane …, 2016 - Springer
The effect of tetracyclic (cortisol, prednisolone, and 9-fluorocortisol acetate) and pentacyclic
(uvaol and erythrodiol) triterpenes (TTPs) on the fluidity of dipalmitoyl phosphatidyl choline …

A comparative study of the effects of cholesterol and sclareol, a bioactive labdane type diterpene, on phospholipid bilayers

I Kyrikou, A Georgopoulos, S Hatziantoniou… - Chemistry and physics …, 2005 - Elsevier
Sclareol (labd-14-ene-8, 13-diol) is a highly water-insoluble molecule that belongs to the
labdane type diterpenes and is characterized as a biologically active molecule, due to its …