Retinal vascular endothelial cell dysfunction and neuroretinal degeneration in diabetic patients

M Mrugacz, A Bryl, K Zorena - Journal of clinical medicine, 2021 - mdpi.com
Diabetes mellitus (DM) has become a vital societal problem as epidemiological studies
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …

Inflammation and retinal degenerative diseases

G Kaur, NK Singh - Neural Regeneration Research, 2023 - journals.lww.com
Vision is an ability that depends on the precise structure and functioning of the retina. Any
kind of stress or injury can disrupt the retinal architecture and leads to vision impairment …

The effect of sodium-glucose cotransporter 2 inhibitors on biomarkers of inflammation: A systematic review and meta-analysis of randomized controlled trials

D Wang, J Liu, L Zhong, S Li, L Zhou… - Frontiers in …, 2022 - frontiersin.org
Aims: Inflammatory biomarkers may play vital roles in the pathophysiology of diabetes and
diabetic cardiorenal complications. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have …

Immune cell landscape of patients with diabetic macular edema by single-cell RNA analysis

P Ma, P Zhang, S Chen, W Shi, J Ye, S Chen… - Frontiers in …, 2021 - frontiersin.org
Purpose: We performed single-cell RNA sequencing (scRNA-seq), an unbiased and high-
throughput single cell technology, to determine phenotype and function of peripheral …

A cross-sectional study to correlate antioxidant enzymes, oxidative stress and inflammation with prevalence of hypertension

S Kaur, S Kaur, A Kaur, S Kaur, S Gupta, S Mittal… - Life Sciences, 2023 - Elsevier
Aims Hypertension a multifactorial consequence of environmental factors, life style and
genetics is the well-recognized risk factor contributing to coronary heart diseases. The …

Novel biomarkers for prognosticating diabetic kidney disease progression

SM Swaminathan, IR Rao, SV Shenoy… - … Urology and Nephrology, 2023 - Springer
The global burden of diabetic kidney disease (DKD) is escalating, and it remains as a
predominant cause of the end-stage renal disease (ESRD). DKD is associated with …

Association of the endothelial nitric oxide synthase (eNOS) 4a/b polymorphism with the risk of incident diabetic retinopathy in patients with type 2 diabetes mellitus: a …

Y Shi, X Fan, K Zhang, Y Ma - Annals of Medicine, 2023 - Taylor & Francis
Objective To conduct a systematic review and updated meta-analysis on the potential
association between endothelial nitric oxide synthase (eNOS) 4a/b polymorphism and the …

Natural plant medications for the treatment of retinal diseases: the blood-retinal barrier as a clue

Y Ren, H Liang, M Xie, M Zhang - Phytomedicine, 2024 - Elsevier
Background Retinal diseases significantly contribute to the global burden of visual
impairment and blindness. The occurrence of retinal diseases is often accompanied by …

Efficacy and safety of intraperitoneal bevacizumab combined with hyperthermic intraperitoneal chemotherapy in the treatment of patients with ovarian cancer and …

M Zhang, Y Bao, H Zhang, D Li, X Mei… - Journal of Obstetrics …, 2023 - Taylor & Francis
Peritoneal effusion is a common event in ovarian cancer (OC) patients. LncRNA H19 and
vascular endothelial growth factor (VEGF) are implicated in cancer progression. The study …

Lab-on-a-chip technologies for minimally invasive molecular sensing of diabetic retinopathy

M Vieira, R Fernandes, AF Ambrósio, V Cardoso… - Lab on a Chip, 2022 - pubs.rsc.org
Diabetic retinopathy (DR) is the most common diabetic eye disease and the worldwide
leading cause of vision loss in working-age adults. It progresses from mild to severe non …