Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?
The field of immunology has traditionally focused on immune checkpoint modulation of
adaptive immune cells. However, many malignancies such as glioblastoma are mostly …
adaptive immune cells. However, many malignancies such as glioblastoma are mostly …
CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy
J Qu, B Wu, L Chen, Z Wen, L Fang, J Zheng… - Journal of Experimental …, 2024 - Springer
Background Mucosal-associated invariant T (MAIT) cells have been reported to regulate
tumor immunity. However, the immune characteristics of MAIT cells in non-small cell lung …
tumor immunity. However, the immune characteristics of MAIT cells in non-small cell lung …
A co-culture model to study modulators of tumor immune evasion through scalable arrayed CRISPR-interference screens
R Martinez, C Finocchiaro, L Delhaye… - Frontiers in …, 2024 - frontiersin.org
Cancer cells effectively evade immune surveillance, not only through the well-known PD-
1/PD-L1 pathway but also via alternative mechanisms that impair patient response to …
1/PD-L1 pathway but also via alternative mechanisms that impair patient response to …
Syngeneic murine models with distinct immune microenvironments represent subsets of human intrahepatic cholangiocarcinoma
Background & Aims Cholangiocarcinoma (CCA) is a poorly immunogenic malignancy
associated with limited survival. Syngeneic immunocompetent mouse models of CCA are an …
associated with limited survival. Syngeneic immunocompetent mouse models of CCA are an …
[PDF][PDF] Charakterystyka wybranych inhibitorów immunologicznych punktówkontrolnych
E Żyła - 2023 - ruj.uj.edu.pl
Układ odpornościowy pełni funkcję ochrony organizmu przed pochodzącymi z zewnątrz
patogenami, ale również przed własnymi komórkami, które wykazują nieprawidłowe cechy …
patogenami, ale również przed własnymi komórkami, które wykazują nieprawidłowe cechy …
Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
F Lin, S Yin, Z Zhang, Y Yu, H Fang, Z Liang, R Zhu… - Cell, 2024 - cell.com
Although immunotherapy has revolutionized cancer treatment, its efficacy is affected by
multiple factors, particularly those derived from the complexity and heterogeneity of the …
multiple factors, particularly those derived from the complexity and heterogeneity of the …