Strategies for improvement of gamma-aminobutyric acid (GABA) biosynthesis via lactic acid bacteria (LAB) fermentation

S Pannerchelvan, L Rios-Solis, FWF Wong… - Food & Function, 2023 - pubs.rsc.org
Gamma-aminobutyric acid (GABA) is a non-protein amino acid widely distributed in nature
and extensively explored for its numerous physiological functions and effects on metabolic …

Proline Analogues

V Kubyshkin, M Rubini - Chemical Reviews, 2024 - ACS Publications
Within the canonical repertoire of the amino acid involved in protein biogenesis, proline
plays a unique role as an amino acid presenting a modified backbone rather than a side …

Mechanism of action of the toxic proline mimic azetidine 2‐carboxylic acid in plants

W Thives Santos, V Dwivedi, H Ngoc Duong… - The Plant …, 2024 - Wiley Online Library
Plants have an amazing capacity to outcompete neighboring organisms for space and
resources. Toxic metabolites are major players in these interactions, which can have a …

[HTML][HTML] A comprehensive review of the proline mimic azetidine-2-carboxylic acid (A2C)

KJ Rodgers, J Kabalan, CR Phillips - Toxicology, 2024 - Elsevier
The imino acid azetidine-2-carboxylic acid (A2C), a proline homologue, was first identified in
liliaceous plants in 1955. Its ability to exchange for proline in protein synthesis is responsible …

Biosyntheses of azetidine-containing natural products

L Pang, D Yao, F Gao, X Bian, Y Zhang… - Organic & Biomolecular …, 2023 - pubs.rsc.org
Azetidine is a four-membered polar heterocycle including a basic secondary amine, and is
characterized by the high ring-strain energy, strong molecular rigidity as well as satisfactory …

Azetidine-2-carboxylic acid-induced oligodendrogliopathy: relevance to the pathogenesis of multiple sclerosis

RA Sobel, M Albertelli, JR Hinojoza… - … of Neuropathology & …, 2022 - academic.oup.com
The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans
and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro. To …

Mode of action of the toxic proline mimic azetidine 2-carboxylic acid in plants

WT Santos, V Dwivedi, HN Duong, M Miederhoff… - bioRxiv, 2024 - biorxiv.org
Plants have an amazing capacity to outcompete neighboring organisms for space and
resources. Toxic metabolites are major players in these interactions, which can have a …

Quantitative Analysis of Aspergillus nidulans Growth Rate using Live Microscopy and Open-Source Software

A Athanasopoulos, A Biratsi, C Gournas… - JoVE (Journal of …, 2021 - jove.com
It is well established that colony growth of filamentous fungi, mostly dependent on changes
in hyphae/mycelia apical growth rate, is macroscopically estimated on solidified media by …