Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020 - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
Human brain effects of DMT assessed via EEG-fMRI
C Timmermann, L Roseman… - Proceedings of the …, 2023 - National Acad Sciences
Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …
The subjective effects of psychedelics may not be necessary for their enduring therapeutic effects
DE Olson - ACS Pharmacology & Translational Science, 2020 - ACS Publications
Psychedelics represent one of the most promising classes of experimental medicines for the
treatment of neuropsychiatric disorders due to their ability to promote neural plasticity and …
treatment of neuropsychiatric disorders due to their ability to promote neural plasticity and …
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies
KAA Andersen, R Carhart‐Harris… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects
Growing interest has been seen in using lysergic acid diethylamide (LSD) and psilocybin in
psychiatric research and therapy. However, no modern studies have evaluated differences …
psychiatric research and therapy. However, no modern studies have evaluated differences …
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
Rationale Recent clinical trials are reporting marked improvements in mental health
outcomes with psychedelic drug-assisted psychotherapy. Objectives Here, we report on …
outcomes with psychedelic drug-assisted psychotherapy. Objectives Here, we report on …
Quality of acute psychedelic experience predicts therapeutic efficacy of psilocybin for treatment-resistant depression
Introduction: It is a basic principle of the “psychedelic” treatment model that the quality of the
acute experience mediates long-term improvements in mental health. In the present paper …
acute experience mediates long-term improvements in mental health. In the present paper …
Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels
MK Madsen, PM Fisher, D Burmester… - …, 2019 - nature.com
The main psychedelic component of magic mushrooms is psilocybin, which shows promise
as a treatment for depression and other mental disorders. Psychedelic effects are believed …
as a treatment for depression and other mental disorders. Psychedelic effects are believed …
[HTML][HTML] Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms
RL Carhart-Harris, L Roseman, M Bolstridge… - Scientific reports, 2017 - nature.com
Psilocybin with psychological support is showing promise as a treatment model in psychiatry
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …