Mathematical models are required to estimate kinetic parameters of [1‐13C] pyruvate‐
lactate interconversion from magnetic resonance spectroscopy data. One‐or two‐way …

In vivo real time spectroscopic imaging of hyperpolarized 13C labeled metabolites shows
substantial promise for the assessment of physiological processes that were previously …

Magnetic resonance imaging and spectroscopy of hyperpolarized (HP) compounds such as
[1-13 C]-pyruvate have shown tremendous potential for offering new insight into disease and …

Over recent years hyperpolarization by dissolution dynamic nuclear polarization has
become an established technique for studying metabolism in vivo in animal models …

Purpose To estimate the rate constant for pyruvate to lactate conversion in tumours in
response to a hypoxic challenge, using hyperpolarised 13 C 1-pyruvate and magnetic …

Dissolution dynamic nuclear polarisation (dDNP) of 13C‐labelled pyruvate in magnetic
resonance spectroscopy/imaging (MRS/MRSI) has the potential for monitoring tumour …

Magnetic resonance (MR)-hyperpolarization based on dynamic nuclear polarization
provides a strongly increased signal intensity allowing real-time metabolic spectroscopic …

Injection process is essential for many industrial applications especially in water
desalination and water treatment market. The new concept of injection, line bleeding …

I cannot express enough gratitude to my committee for guiding me through this learning
process: Dr. James Bankson, my committee chair; Dr. Jason Stafford; Ms. Donna Reeve; Dr …

There has been recent interest in using hyperpolarised 13 C 1-pyruvate for studying cancer
metabolism. The methodology has been used to study the effect of dichloroacetate (DCA) on …