The cardiovascular and other actions of angiotensin II (Ang II) are mediated by AT1 and AT2
receptors, which are seven transmembrane glycoproteins with 30% sequence similarity …

Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes
renin, angiotensin-converting enzyme (ACE), and aminopeptidases A and N may all be …

I. Introduction A ngiotensin (ANG II) was discovered about 50 yr ago (1, 2), and a complete
peripheral system for the formation and metabolism of ANG II was soon characterized. It was …

Angiotensin II is known primarily for its effects on blood pressure and electrolyte
homeostasis, but recent studies suggest that angiotensin II may play a role in the regulation …

Abstract Angiotensin II (Ang II) exerts a number of central actions on fluid and electrolyte
homeostasis, autonomic activity, and neuroendocrine regulation. In order to evaluate likely …

Considerable evidence now suggests that the precursors and enzymes necessary for the
formation and degradation of biologically active forms of angiotensins are present in brain …

In addition to its traditional role as a circulating hormone, angiotensin is also involved in
local functions through the activity of tissue renin-angiotensin systems that occur in many …

This review summarizes emerging evidence that supports the notion of a separate brain
renin-angiotensin system (RAS) complete with the necessary precursors and enzymes for …

The present research characterizes a newly discovered ANG II (3–8)(ANG IV) binding site
localized in structures associated with memory function (hippocampus, neocortex …

Considerable evidence now indicates that a separate and distinct renin-angiotensin system
(RAS) is present within the brain. The necessary precursors and enzymes required for the …