Small heat shock proteins: Simplicity meets complexity
M Haslbeck, S Weinkauf, J Buchner - Journal of Biological Chemistry, 2019 - ASBMB
Small heat shock proteins (sHsps) are a ubiquitous and ancient family of ATP-independent
molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso …
molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso …
[HTML][HTML] Small heat shock proteins: role in cellular functions and pathology
Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development
Q Wan, D Song, H Li, M He - Signal transduction and targeted therapy, 2020 - nature.com
Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
Molecular signatures of beef tenderness: Underlying mechanisms based on integromics of protein biomarkers from multi-platform proteomics studies
Over the last two decades, proteomics have been employed to decipher the underlying
factors contributing to variation in the quality of muscle foods, including beef tenderness …
factors contributing to variation in the quality of muscle foods, including beef tenderness …
Heat shock proteins in toxicology: how close and how far?
The response to stress triggers activation of the genes involved in cell survival and/or cell
death. Stress response is a ubiquitous feature of cells that is induced under stress …
death. Stress response is a ubiquitous feature of cells that is induced under stress …
HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy
X Wang, M Chen, J Zhou… - … journal of oncology, 2014 - spandidos-publications.com
Among the heat shock proteins (HSP), HSP27, HSP70 and HSP90 are the most studied
stress-inducible HSPs, and are induced in response to a wide variety of physiological and …
stress-inducible HSPs, and are induced in response to a wide variety of physiological and …
Large potentials of small heat shock proteins
EV Mymrikov, AS Seit-Nebi… - Physiological …, 2011 - journals.physiology.org
Modern classification of the family of human small heat shock proteins (the so-called HSPB)
is presented, and the structure and properties of three members of this family are analyzed …
is presented, and the structure and properties of three members of this family are analyzed …
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer
Aberrations in nuclear size and shape are commonly used to identify cancerous tissue.
However, it remains unclear whether the disturbed nuclear structure directly contributes to …
However, it remains unclear whether the disturbed nuclear structure directly contributes to …
Crystal structure and assembly of a eukaryotic small heat shock protein
RLM Van Montfort, E Basha, KL Friedrich… - Nature structural …, 2001 - nature.com
The 2.7 Å structure of wheat HSP16. 9, a member of the small heat shock proteins (sHSPs),
indicates how its α-crystallin domain and flanking extensions assemble into a dodecameric …
indicates how its α-crystallin domain and flanking extensions assemble into a dodecameric …
[HTML][HTML] The growing world of small heat shock proteins: from structure to functions
S Carra, S Alberti, PA Arrigo, JL Benesch… - Cell Stress and …, 2017 - Elsevier
Small heat shock proteins (sHSPs) are present in all kingdoms of life and play fundamental
roles in cell biology. sHSPs are key components of the cellular protein quality control …
roles in cell biology. sHSPs are key components of the cellular protein quality control …