[HTML][HTML] An overview of the public health challenges in diagnosing and controlling human foodborne pathogens
Pathogens found in food are believed to be the leading cause of foodborne illnesses; and
they are considered a serious problem with global ramifications. During the last few …
they are considered a serious problem with global ramifications. During the last few …
Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment
B Feng, F Chu, A Bi, X Huang, Y Fang, M Liu… - Biotechnology …, 2023 - Elsevier
Abstract Beta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …
Dual-parameter recognition-directed design of the activatable fluorescence probe for precise imaging of cellular senescence
J Li, L Wang, X Luo, Y Xia, Y Xie, Y Liu… - Analytical …, 2023 - ACS Publications
Specific imaging of cellular senescence emerges as a promising strategy for early diagnosis
and treatment of various age-related diseases. The currently available imaging probes are …
and treatment of various age-related diseases. The currently available imaging probes are …
Chemical Strategies for the Detection and Elimination of Senescent Cells
J García-Fleitas, A García-Fernández… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Cellular senescence can be defined as an irreversible stopping of cell
proliferation that arises in response to various stress signals. Cellular senescence is …
proliferation that arises in response to various stress signals. Cellular senescence is …
[HTML][HTML] Current scenario of pathogen detection techniques in agro-food sector
Over the past-decade, agricultural products (such as vegetables and fruits) have been
reported as the major vehicles for foodborne diseases, which are limiting food resources …
reported as the major vehicles for foodborne diseases, which are limiting food resources …
A molecular imaging tool for monitoring carboxylesterase 2 during early diagnosis of liver-related diseases
J Li, J Cao, W Wu, L Xu, S Zhang, P Ma, Q Wu… - Sensors and Actuators B …, 2023 - Elsevier
Early disease diagnosis is crucial for human health and successful therapy.
Carboxylesterase 2 (CES2), the main enzyme found in many tumor tissues, is closely …
Carboxylesterase 2 (CES2), the main enzyme found in many tumor tissues, is closely …
Detection and Elimination of Senescent Cells with a Self-Assembled Senescence-Associated β-Galactosidase-Activatable Nanophotosensitizer
Senescent cells have become an important therapeutic target for many age-related
dysfunctions and diseases. We report herein a novel nanophotosensitizing system that is …
dysfunctions and diseases. We report herein a novel nanophotosensitizing system that is …
[HTML][HTML] A renal clearable fluorogenic probe for in vivo β-galactosidase activity detection during aging and senolysis
S Rojas-Vázquez, B Lozano-Torres… - Nature …, 2024 - nature.com
Accumulation of senescent cells with age leads to tissue dysfunction and related diseases.
Their detection in vivo still constitutes a challenge in aging research. We describe the …
Their detection in vivo still constitutes a challenge in aging research. We describe the …
An iminocoumarin based covalent-assembly red-emitting fluorescent probe for detection of β-galactosidase activity in ovarian cancer cells
YC Ku, PH Lin, CY Huang, CW Lee, CH Yu, SC Chen… - Dyes and …, 2023 - Elsevier
Upregulation of β-Galactosidase (β-Gal) has been generally found in primary ovarian cancer
cells, making the intra-cellular β-Gal as a valuable biomarker for related tumors. In this study …
cells, making the intra-cellular β-Gal as a valuable biomarker for related tumors. In this study …
[HTML][HTML] Developing a far-red fluorogenic beta-galactosidase probe for senescent cell imaging and photoablation
A methylene blue (MB)-based beta-galactosidase (β-gal) activatable molecule, Gal-MB, was
developed for senescence imaging and light-triggered senolysis. When in contact with LacZ …
developed for senescence imaging and light-triggered senolysis. When in contact with LacZ …