Pathogens found in food are believed to be the leading cause of foodborne illnesses; and
they are considered a serious problem with global ramifications. During the last few …

Abstract Beta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …

Specific imaging of cellular senescence emerges as a promising strategy for early diagnosis
and treatment of various age-related diseases. The currently available imaging probes are …

Conspectus Cellular senescence can be defined as an irreversible stopping of cell
proliferation that arises in response to various stress signals. Cellular senescence is …

Over the past-decade, agricultural products (such as vegetables and fruits) have been
reported as the major vehicles for foodborne diseases, which are limiting food resources …

Early disease diagnosis is crucial for human health and successful therapy.
Carboxylesterase 2 (CES2), the main enzyme found in many tumor tissues, is closely …

Senescent cells have become an important therapeutic target for many age-related
dysfunctions and diseases. We report herein a novel nanophotosensitizing system that is …

Accumulation of senescent cells with age leads to tissue dysfunction and related diseases.
Their detection in vivo still constitutes a challenge in aging research. We describe the …

Upregulation of β-Galactosidase (β-Gal) has been generally found in primary ovarian cancer
cells, making the intra-cellular β-Gal as a valuable biomarker for related tumors. In this study …

A methylene blue (MB)-based beta-galactosidase (β-gal) activatable molecule, Gal-MB, was
developed for senescence imaging and light-triggered senolysis. When in contact with LacZ …