It is evident that in the last decade or so, a vast amount of new information has become
available concerning the various 5-HT receptor types and their characteristics. This derives …

These studies in anaesthetised rats showed, using intravital microscopy, that the novel anti-
migraine agent, rizatriptan, significantly reduced electrically stimulated dural vasodilation but …

Vasodilatation in the dura mater has been implicated in migraine pathogenesis. Anti‐
migraine triptan drugs block vasodilatation by binding to 5‐HT1B/1D receptors localized on …

Dural plasma extravasation produced by electrical stimulation of the trigeminal ganglion was
measured in rats and the concomitant expression of c-fos mRNA produced in the trigeminal …

Previous studies in the developing mouse thalamus have demonstrated that regional
identity is established during early stages of development (Suzuki-Hirano et al. J. Comp …

These studies compared the effects of the 5-HT1B/1D receptor agonists sumatriptan, CP-
122 288 ((R)-N-methyl-[3-(1-methyl-2-pyrrolidinylmethyl)-1H-indol-5-yl] …

The type of trigeminal ganglion cells that express 5-HT1B receptors has not been well
characterized, despite the fact that these receptors are important targets for anti-migraine …

The anti-migraine drug, eletriptan [(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-
(phenylsulphonyl) ethyl]-1H-indole; UK-116,044], is a novel 5-HT1B/1D receptor agonist. In …

1 The aim of the present study was to investigate the in vivo pharmacological profile of CP‐
122, 288, an indole‐derivative with a conformationally restricted N‐methylpyrrolidinyl basic …

DE CASTRO-E-SILVA, E., C. SARMENTO, TA NASCIMENTO, CP LUZ, T. SOARES, CA
MARINHO, M. CUNHA, C. BULCÃO, IR DE OLIVEIRA AND JB FREGONEZE. Effect of third …