Smart Nanoscale Extracellular Vesicles in the Brain: Unveiling their Biology, Diagnostic Potential, and Therapeutic Applications

A Onkar, F Khan, A Goenka… - … Applied Materials & …, 2024 - ACS Publications
Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …

Noncoding RNAs: emerging regulators of behavioral complexity

S Dayal, D Chaubey, DC Joshi… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The mammalian genome encodes thousands of non− coding RNAs (ncRNAs), ranging in
size from about 20 nucleotides (microRNAs or miRNAs) to kilobases (long non− coding …

[HTML][HTML] The microRNA profile of brain-derived extracellular vesicles: A promising step forward in developing pharmacodynamic biomarkers for psychiatric disorders

MO Kohshour, U Heilbronner, T Mueller… - European …, 2025 - Elsevier
MicroRNAs (miRNAs) have the potential to affect drug metabolism, and some drugs affect
cellular miRNA expression. miRNAs are found inside extracellular vesicles (EVs), and the …

Psychotic Disorders and exosomes: an overview of current evidence and future directions

C Desmeules, O Corbeil, M Huot-Lavoie, L Béchard… - Psychiatry …, 2024 - Elsevier
Due to its reliance on heterogeneous symptomatology, the accurate diagnosis of psychotic
disorders remains a challenging task in clinical practice. Precise and early diagnosis of …

Identification of markers for the isolation of neuron-specific extracellular vesicles

D Ter-Ovanesyan, S Whiteman, T Gilboa, EJK Kowal… - bioRxiv, 2024 - biorxiv.org
Extracellular vesicles (EVs) are released by all cells and contain RNA and protein from their
cell of origin. EVs in biofluids could be used as diagnostic biomarkers to non-invasively …

The improved de Bruijn graph for multitask learning: predicting functions, subcellular localization, and interactions of noncoding RNAs

Y Wei, Q Zhang, L Liu - Briefings in Bioinformatics, 2025 - academic.oup.com
Noncoding RNA refers to RNA that does not encode proteins. The lncRNA and miRNA it
contains play crucial regulatory roles in organisms, and their aberrant expression is closely …

Newborn reactions to maternal prenatal stress alter umbilical cord blood tRNA fragments targeting cholinergic transcripts

SV Treidel, SM Lobmaier, R Sharma, N Madrer… - bioRxiv, 2024 - biorxiv.org
Maternal perceived prenatal stress (PPS) is a known risk factor for diverse developmental
impairments in newborns, but the underlying molecular processes are incompletely …

The roles of extracellular vesicle-derived microRNAs in schizophrenia: A scoping review.

R Zhang, X Lei, J Ren, C Zhang - 2024 - psycnet.apa.org
This letter presents a review of the literature on the roles of extracellular vesicle (EV)-derived
micrornas (miRNAs) in schizophrenia. The current literature revealed abnormal expression …

Nörotensin geninin 3'kodlama yapmayan bölgesindeki sekans varyantlarının şizofreni ile ilişkilerinin araştırılması

E Boztepe - 2024 - acikerisim.uludag.edu.tr
Şizofreni (SCZ), dünya çapında nüfusun% 1'ini etkileyen karmaşık nöropsikiyatrik bir
bozukluktur. SCZ'nin etiyolojisi, çevresel ve genetik faktörlerin etkileşimi ile açıklanmaktadır …

Profiling cargo of brain extracellular vesicles in individuals with depression

P Ibrahim - 2024 - search.proquest.com
Major depressive disorder (MDD) is a leading cause of disability with significant mortality
risk. Despite progress in our understanding of the etiology of MDD, the underlying molecular …