Growing evidence suggests that thrombophilia is associated with venous thromboembolism
(VTE) and adverse pregnancy outcomes. However, methodological limitations have made it …

Abstract The enzyme 5, 10-methylenetetrahydrofolate reductase (MTHFR) is involved in
folate metabolism. The MTHFR gene is located on chromosome 1 (1p36. 3), and two …

ABSTRACT Background: In India, most people adhere to a vegetarian diet, which may lead
to cobalamin deficiency. Objective: The objective was to examine indicators of cobalamin …

Elevated plasma total homocysteine (tHcy) is a risk factor for occlusive cardiovascular
disease (CVD). This concept is based on the observations of premature vascular disease in …

Reduction of 5, 10-methylenetetrahydrofolate (methyleneTHF), a donor for methylating
dUMP to dTMP in DNA synthesis, to 5-methyltetrahydrofolate (methylTHF), the primary …

A common genetic polymorphism results from a C→ T substitution in the gene encoding
methylenetetrahydrofolate reductase (MTHFR), the enzyme that produces 5 …

Venous thrombosis, whose main clinical presentations include deep vein thrombosis and
pulmonary embolism, represents a major health problem worldwide. Numerous conditions …

Nygård O, Vollset SE, Refsum H, Brattström L, Ueland PM (University of Bergen, Norway;
County Hospital, Kalmar, Sweden). Total homocysteine and cardiovascular disease …

Vascular diseases are commonly associated with traditional risk factors, but in the last
decade scientific evidence has suggested that elevated plasma levels of homocysteine are …

Background—Data are conflicting concerning ischemic stroke risk associated with a
common polymorphism in the gene encoding 5, 10-methylenetetrahydrofolate reductase …