Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

A Chadt, H Al-Hasani - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
A family of facilitative glucose transporters (GLUTs) is involved in regulating tissue-specific
glucose uptake and metabolism in the liver, skeletal muscle, and adipose tissue to ensure …

[HTML][HTML] Growth factor control of pancreatic islet regeneration and function

A Assmann, C Hinault, RN Kulkarni - Pediatric diabetes, 2009 - ncbi.nlm.nih.gov
Type 1 and type 2 diabetes mellitus together are predicted to affect over 300 million people
worldwide by the year 2020. A relative or absolute paucity of functional β-cells is a central …

[HTML][HTML] Metabolic impairments and tissue disorders in alloxan-induced diabetic rats are alleviated by Salvia officinalis L. essential oil

S Belhadj, O Hentati, M Hammami, AB Hadj… - Biomedicine & …, 2018 - Elsevier
The current research explored for the first time the effect of Salvia officinalis L.(Sage)
essential oil (EO) on Alloxan-induced diabetes in male Wistar rats. Sage EO was extracted …

Pancreatic atrophy caused by dietary selenium deficiency induces hypoinsulinemic hyperglycemia via global down-regulation of selenoprotein encoding genes in …

J Xu, L Wang, J Tang, G Jia, G Liu, X Chen, J Cai… - PLoS …, 2017 - journals.plos.org
This study was envisaged to comprehensively profile genes in selected tissues along with a
few biochemical indicators and integrate resulting information with dietary selenium (Se) …

The transcription factor Rfx3 regulates β-cell differentiation, function, and glucokinase expression

A Ait-Lounis, C Bonal, Q Seguín-Estévez… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Pancreatic islets of perinatal mice lacking the transcription factor Rfx3 exhibit a
marked reduction in insulin-producing β-cells. The objective of this work was to unravel the …

HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters

D Kasai, T Adachi, L Deng, M Nagano-Fujii, K Sada… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: Persistent infection with hepatitis C virus (HCV) causes extrahepatic
diseases, including diabetes. We investigated the possible effect (s) of HCV replication on …

Cocoa-rich diet ameliorates hepatic insulin resistance by modulating insulin signaling and glucose homeostasis in Zucker diabetic fatty rats

I Cordero-Herrera, MÁ Martín, F Escrivá… - The journal of nutritional …, 2015 - Elsevier
Insulin resistance is the primary characteristic of type 2 diabetes and results from insulin
signaling defects. Cocoa has been shown to exert anti-diabetic effects by lowering glucose …

The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism

CH Samanez, S Caron, O Briand… - … of physiology and …, 2012 - Taylor & Francis
Metabolic diseases reach epidemic proportions. A better knowledge of the associated
alterations in the metabolic pathways in the liver is necessary. These studies need in vitro …

Disruption of HIF-1α in hepatocytes impairs glucose metabolism in diet-induced obesity mice

D Ochiai, N Goda, T Hishiki, M Kanai… - Biochemical and …, 2011 - Elsevier
The liver plays a central role in glucose homeostasis in the whole-body by responding to
environmental factors including nutrients, hormones, and oxygen. In conditions of metabolic …

Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study

TE Meyer, E Boerwinkle, AC Morrison, KA Volcik… - … , biomarkers & prevention, 2010 - AACR
There is a known inverse association between type 2 diabetes (T2D) and prostate cancer
(PrCa) that is poorly understood. Genetic studies of the T2D-PrCa association may provide …