Green recipes to quinoline: A review

LM Nainwal, S Tasneem, W Akhtar, G Verma… - European Journal of …, 2019 - Elsevier
The quinoline core possesses a vast number of biological activities such as anticancer,
antimalarial, antimicrobial, antifungal, antitubercular and antileishmanial. The conventional …

Current strategies in development of new chromone derivatives with diversified pharmacological activities: A review

NA Mohsin, M Irfan, S Hassan, U Saleem - Pharmaceutical chemistry …, 2020 - Springer
Chromone derivatives possess a spectrum of biological activities. Chromone has been
recognized as a privileged structure for new drug invention and development. Substitution …

Synthesis, characterization, and biological activities of novel vanadium (IV) and cobalt (II) complexes

T Damena, D Zeleke, T Desalegn, TB Demissie… - ACS …, 2022 - ACS Publications
Herein, we report novel Co (II) and V (IV) complexes synthesized from an (E)-2-(((2-((2-
hydroxyethyl) amino) quinolin-3-yl) methylene) amino) ethan-1-ol ligand (L), cobalt (II) …

Chromone, a privileged scaffold in drug discovery: Developments in the synthesis and bioactivity

AT Benny, SD Arikkatt, CG Vazhappilly… - Mini Reviews in …, 2022 - ingentaconnect.com
Chromones are the class of secondary metabolites that broadly occur in the plant kingdom
in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged …

Recent advancements in anti-leishmanial research: Synthetic strategies and structural activity relationships

O Gupta, T Pradhan, R Bhatia, V Monga - European Journal of Medicinal …, 2021 - Elsevier
Leishmaniasis is a parasitic neglected tropical disease caused by various species of
Leishmania parasite. Despite tremendous advancements in the therapeutic sector and drug …

Design, synthesis and biological evaluation of 8-aminoquinoline-1, 2, 3-triazole hybrid derivatives as potential antimicrobial agents

F Albayrak, M Çiçek, D Alkaya, I Kulu - Medicinal Chemistry Research, 2022 - Springer
A library of 20 novel quinoline-1, 2, 3-triazole hybrid compounds were synthesized by
starting from 8-aminoquinoline to discover new pharmacophores exhibiting antimicrobial …

Quinoline: a promising scaffold in recent antiprotozoal drug discovery

A Dorababu - ChemistrySelect, 2021 - Wiley Online Library
Protozoal infections malaria and leishmania have become most prevalent in recent times. A
high death rate is reported world‐wide because of these diseases. Although there are only a …

Identification of quinoline-chalcones and heterocyclic chalcone-appended quinolines as broad-spectrum pharmacological agents

D Atukuri, S Vijayalaxmi, R Sanjeevamurthy, L Vidya… - Bioorganic …, 2020 - Elsevier
Quinoline derivatives have been reported to possess enticing pharmacological properties. In
particular, quinoline-chalcones are identified as promising scaffolds for drug discovery. For a …

Synthesis and chemopreventive potential of 5-fu/genistein hybrids on colorectal cancer cells

G Moreno-Quintero, W Castrillón-Lopez… - Pharmaceuticals, 2022 - mdpi.com
A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by
spectroscopic analysis. The chemopreventive potential of these compounds was evaluated …

New thiazolyl‐pyrazoline derivatives bearing nitrogen mustard as potential antimicrobial and antiprotozoal agents

V Cuartas, SM Robledo, ID Vélez… - Archiv der …, 2020 - Wiley Online Library
A new series of N‐substituted pyrazoline derivatives 6a–g, 7a–g, 8a–g, and 9a–g was
synthetized by reaction of hydrazine derivatives and chalcone–thiazole hybrids bearing …