Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection

M Castanheira, PJ Simner… - JAC-antimicrobial …, 2021 - academic.oup.com
Extended-spectrum β-lactamase (ESBL)-producing Gram-negative pathogens are a major
cause of resistance to expanded-spectrum β-lactam antibiotics. Since their discovery in the …

Extended-spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options

G Peirano, JDD Pitout - Drugs, 2019 - Springer
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are a major global
public health concern. Presently, Escherichia coli with CTX-Ms are the most common …

[HTML][HTML] European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram …

M Paul, E Carrara, P Retamar, T Tängdén… - Clinical Microbiology …, 2022 - Elsevier
Scope These ESCMID guidelines address the targeted antibiotic treatment of third-
generation cephalosporin-resistant Enterobacterales (3GCephRE) and carbapenem …

[HTML][HTML] Molecular Mechanisms, Epidemiology, and Clinical Importance of β-Lactam Resistance in Enterobacteriaceae

G De Angelis, P Del Giacomo, B Posteraro… - International journal of …, 2020 - mdpi.com
Despite being members of gut microbiota, Enterobacteriaceae are associated with many
severe infections such as bloodstream infections. The β-lactam drugs have been the …

[HTML][HTML] Detection of antibiotic-resistance by MALDI-TOF mass spectrometry: an expanding area

W Florio, L Baldeschi, C Rizzato, A Tavanti… - Frontiers in cellular …, 2020 - frontiersin.org
Several MALDI-TOF MS-based methods have been proposed for rapid detection of
antimicrobial resistance. The most widely studied methods include assessment of β …

Variation of effect estimates in the analysis of mortality and length of hospital stay in patients with infections caused by bacteria-producing extended-spectrum beta …

P Shamsrizi, BP Gladstone, E Carrara, D Luise… - BMJ open, 2020 - bmjopen.bmj.com
Objective To assess the variation of effect estimates in the analysis of mortality and length of
stay (LOS) in patients with infections caused by extended-spectrum beta-lactamase (ESBL) …

Development and validation of BLOOMY prediction scores for 14-day and 6-month mortality in hospitalised adults with bloodstream infections: a multicentre …

E Tacconelli, S Göpel, BP Gladstone… - The Lancet Infectious …, 2022 - thelancet.com
Background The burden of bloodstream infections remains high worldwide and cannot be
confined to short-term in-hospital mortality. We aimed to develop scores to predict short-term …

[HTML][HTML] Nosocomial infections due to multidrug-resistant bacteria in cancer patients: a six-year retrospective study of an oncology Center in Western China

AM Jiang, X Shi, N Liu, H Gao, MD Ren… - BMC infectious …, 2020 - Springer
Background Bacterial infections are the most frequent complications in patients with
malignancy, and the epidemiology of nosocomial infections among cancer patients has …

[HTML][HTML] Fighting AMR in the healthcare environment: microbiome-based sanitation approaches and monitoring tools

M D'Accolti, I Soffritti, S Mazzacane… - International journal of …, 2019 - mdpi.com
Healthcare-associated infections (HAIs) affect up to 15% of all hospitalized patients,
representing a global concern. Major causes include the persistent microbial contamination …

How to tailor recommendations on the treatment of multi-drug resistant Gram-negative infections at country level integrating antibiotic stewardship principles within the …

E Carrara, PA Grossi, A Gori… - The Lancet Infectious …, 2024 - thelancet.com
Promoting the optimal use of antibiotics through evidence-based recommendations should
be regarded as a crucial step in the global fight against antimicrobial resistance. Within this …