The hnRNP family: insights into their role in health and disease

T Geuens, D Bouhy, V Timmerman - Human genetics, 2016 - Springer
Heterogeneous nuclear ribonucleoproteins (hnRNPs) represent a large family of RNA-
binding proteins (RBPs) that contribute to multiple aspects of nucleic acid metabolism …

Clinical and pathologic features of congenital myasthenic syndromes caused by 35 genes—a comprehensive review

K Ohno, B Ohkawara, XM Shen, D Selcen… - International journal of …, 2023 - mdpi.com
Congenital myasthenic syndromes (CMS) are a heterogeneous group of disorders
characterized by impaired neuromuscular signal transmission due to germline pathogenic …

Handshakes and fights: the regulatory interplay of RNA-binding proteins

E Dassi - Frontiers in molecular biosciences, 2017 - frontiersin.org
What drives the flow of signals controlling the outcome of post-transcriptional regulation of
gene expression? This regulatory layer, presiding to processes ranging from splicing to …

Rules and tools to predict the splicing effects of exonic and intronic mutations

K Ohno, J Takeda, A Masuda - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Development of next generation sequencing technologies has enabled detection of
extensive arrays of germline and somatic single nucleotide variations (SNVs) in human …

The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain

S Bhattacharya, MJ Levy, N Zhang, H Li… - Nature …, 2021 - nature.com
Heterogeneous ribonucleoproteins (hnRNPs) are RNA binding molecules that are involved
in key processes such as RNA splicing and transcription. One such hnRNP protein, hnRNP …

Heterogeneous nuclear ribonucleoproteins: implications in neurological diseases

YH Low, Y Asi, SC Foti, T Lashley - Molecular Neurobiology, 2021 - Springer
Heterogenous nuclear ribonucleoproteins (hnRNPs) are a complex and functionally diverse
family of RNA binding proteins with multifarious roles. They are involved, directly or …

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

C Vandermeulen, T O'grady, J Wayet, B Galvan… - PLoS …, 2021 - journals.plos.org
Viral infections are known to hijack the transcription and translation of the host cell.
However, the extent to which viral proteins coordinate these perturbations remains unclear …

Global approaches in studying RNA-binding protein interaction networks

EL Sternburg, FV Karginov - Trends in biochemical sciences, 2020 - cell.com
RNA-binding proteins (RBPs) play crucial roles in almost all aspects of cellular biology. RBP
binding at specific target sites impacts expression of functionally coordinated sets of mRNAs …

Differential RNA packaging into small extracellular vesicles by neurons and astrocytes

X Luo, R Jean-Toussaint, A Sacan, SK Ajit - Cell Communication and …, 2021 - Springer
Background Small extracellular vesicles (sEVs) mediate intercellular communication by
transferring RNA, proteins, and lipids to recipient cells. These cargo molecules are …

Congenital myasthenic syndromes and the neuromuscular junction

PMR Cruz, J Palace, D Beeson - Current opinion in neurology, 2014 - journals.lww.com
Congenital myasthenic syndromes and the neuromuscular juncti... : Current Opinion in
Neurology Congenital myasthenic syndromes and the neuromuscular junction : Current Opinion …