Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …

Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered
pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset …

Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

Aspirin is currently the most widely prescribed treatment in the prevention of cardiovascular
complications. The indications for the use of aspirin during pregnancy are, however, the …

Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

Preeclampsia is a clinical syndrome defined as the new onset of hypertension and
proteinuria during the second half of pregnancy. 1 It afflicts 3% to 5% of pregnancies and is …

Background The cause of preeclampsia remains unclear. Limited data suggest that excess
circulating soluble fms-like tyrosine kinase 1 (sFlt-1), which binds placental growth factor …