Study Design: PRISMA-guided systematic review. Objectives: To provide a comprehensive
framework of the current animal models for investigating spinal cord injury (SCI) and …

Each of the descending pathways involved in motor control has a number of anatomical,
molecular, pharmacological, and neuroinformatic characteristics. They are differentially …

An inhibitory extracellular milieu and neuron-intrinsic processes prevent axons from
regenerating in the adult central nervous system (CNS). Here we show how the two aspects …

The examination of tissue histology by light microscopy is a fundamental tool for
investigating the structure and function of organs under normal and disease states. Many …

Neural stem cells (NSCs) expressing GFP were embedded into fibrin matrices containing
growth factor cocktails and grafted to sites of severe spinal cord injury. Grafted cells …

Half of human spinal cord injuries lead to chronic paralysis. Here, we introduce an
electrochemical neuroprosthesis and a robotic postural interface designed to encourage …

Damage to the adult CNS often leads to persistent deficits due to the inability of mature
axons to regenerate after injury. Mounting evidence suggests that the glial environment of …

In contrast to peripheral nerves, central axons do not regenerate. Partial injuries to the spinal
cord, however, are followed by functional recovery. We investigated the anatomical basis of …

Diffusion tensor imaging is highly sensitive to the microstructural integrity of the brain and
has uncovered significant abnormalities following traumatic brain injury not appreciated …

Peptide amphiphile (PA) molecules that self-assemble in vivo into supramolecular
nanofibers were used as a therapy in a mouse model of spinal cord injury (SCI). Because …