Anthracycline chemotherapy causes cardiotoxicity, and the evidence regarding the benefit of
concomitant statin use in reducing it remains uncertain. We conducted a meta-analysis of …

Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies.
Oxidative stress has been validated as a critical event involved in DOX-induced …

Anthracycline antibiotics (doxorubicin, daunorubicin, mitoxantrone, idarubicin, epirubicin,
ect.) are widely used in chemotherapy of various diseases, effectively destroying cancer …

The absence of effective therapeutic targets poses considerable obstacles to the treatment
of triple-negative breast cancer (TNBC). This study aimed to explore the function and …

Doxorubicin hydrochloride (DOX) from pharmaceutical industry and daily life can cause
inherent damage to human health and living organisms. The adsorption and removal of …

Streptomyces spp. are “nature's antibiotic factories” that produce valuable bioactive
metabolites, such as the cytotoxic anthracycline polyketides. While the anthracyclines have …

Anthracycline toxicity describes the toxic consequences of anthracycline-class medications.
Anthracyclines, such as doxorubicin and epirubicin, are potent chemotherapy agents …

Background Immunogenic cell death (ICD) is a specific form of regulated cell death induced
by a variety of stressors. During ICD, the dying cancer cells release damage-associated …

Fungi produce various bioactive secondary metabolites (SMs) as protective and
weaponized tools to enhance survival in shared ecological niches. By mimicking a …

The chemotherapy drug doxorubicin (DOX) is an anthracycline with over 30% incidence of
liver injury in breast cancer patients, yet the mechanism of its hepatotoxicity remains unclear …