Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

Human and simian immunodeficiency viruses (HIVs and SIVs, respectively) encode several
small proteins (Vif, Vpr, Nef, Vpu, and Vpx) that are called accessory because they are not …

Summary Many SARS-CoV-2-infected individuals remain asymptomatic. Little is known
about the extent and quality of their antiviral humoral response. Here, we analyze antibody …

Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) are
promising molecules for therapeutic or prophylactic interventions. Beyond neutralization …

Summary While HIV-1-mediated CD4 downregulation protects infected cells from antibody-
dependent cellular cytotoxicity (ADCC), shed gp120 binds to CD4 on uninfected bystander …

Crystallization-induced photoluminescence weakening was recently revealed in ultrasmall
metal nanoparticles. However, the fundamentals of the phenomenon are not understood yet …

The conformation of the HIV-1 envelope glycoprotein (Env) substantially impacts antibody
recognition and antibody-dependent cellular cytotoxicity (ADCC) responses. In the absence …

HIV-1 spreads through contacts between infected and target cells. Polarized viral budding at
the contact site forms the virological synapse. Additional cellular processes, such as …

ABSTRACT HIV-1 envelope glycoprotein (Env) conformation substantially impacts antibody-
dependent cellular cytotoxicity (ADCC). Envs from primary HIV-1 isolates adopt a prefusion …

Antibodies (Abs) are the major component of the humoral immune response and a key
player in vaccination. The precise Ab-mediated inhibitory mechanisms leading to in vivo …