Thioredoxin-interacting protein (TXNIP), widely known as thioredoxin-binding protein 2
(TBP2), is a major binding mediator in the thioredoxin (TXN) antioxidant system, which …

In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). There is currently no single definitive test for MS. Circulating …

Microglia are highly plastic immune cells which exist in a continuum of activation states. By
shaping the function of oligodendrocyte precursor cells (OPCs), the brain cells which …

Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous
system. Foxp3+ regulatory T (Treg) cells are reduced in frequency and dysfunctional in …

Abstract Background Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been
implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic …

Several micro (mi) RNA are deregulated in brain, cerebrospinal fluid (CSF), and
serum/plasma from patients with Alzheimer's disease (AD). The aim of the study was to …

Background and objective Parkinson's disease (PD) is the second most common age-
related neurodegenerative disorder after Alzheimer's disease. The aim of this work was to …

Background Parkinson's disease (PD) is the most common movement disorder among
adults, affecting 2% of the world population older than 65 years of age. No diagnostic …

About 80% of brain disorders have a genetic basis. The pathogenesis of most
neurodegenerative diseases is associated with a myriad of genetic defects, epigenetic …