The emerging trends in the combinatorial chemistry and drug design have led to the
development of drug candidates with greater lipophilicity, high molecular weight and poor …

A surprisingly large proportion of new drug candidates emerging from drug discovery
programmes are water insoluble, and therefore poorly bioavailable, leading to abandoned …

A significant percentage of active pharmaceutical ingredients identified through discovery
screening programs is poorly soluble in water. These molecules are often difficult to …

With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

More than 40% of compounds identified through combinatorial screening programs are
poorly soluble in water. These molecules are difficult to formulate using conventional …

Nanoparticles are a drug delivery platform that can enhance the efficacy of active
pharmaceutical ingredients, including poorly-water soluble compounds, ionic drugs …

Over the past few decades, there has been a considerable research interest in drug
nanocrystal system as a pharmaceutical approach for poorly soluble drugs. At the beginning …

Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently
become one of the most interesting substances in nanopharmaceuticals. NSs have high …

Nanoparticles bring many benefits to pulmonary drug delivery applications, especially for
systemic delivery and drugs with poor solubility. They have recently been explored in …

The aims of the current work included: development of a new production method for
nanoparticles of water-insoluble drugs in combination with lipids, characterization of the …