Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis

Q Wang, B Shen, L Chen, P Zheng, H Feng, Q Hao… - Oncogene, 2015 - nature.com
Extracellular proteins are vital for cell activities, such as cell migration. Calumenin is highly
conserved among eukaryotes, but its functions are largely unclear. Here, we identify …

Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling

L Chen, S Xu, Y Xu, W Lu, L Liu, D Yue, J Teng, J Chen - Oncogene, 2016 - nature.com
Cytosolic Ca 2+, closely related to endoplasmic reticulum (ER) Ca 2+, plays a critical role in
regulating cell proliferation and tumorigenesis. However, the role of ER lumen proteins in …

Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription

H Feng, L Chen, Q Wang, B Shen, L Liu, P Zheng… - Cell Death & …, 2013 - nature.com
Filopodia, which are actin-rich finger-like membrane protrusions, have an important role in
cell migration and tumor metastasis. Here we identify 13 novel calumenin (Calu) isoforms …

The intracellular transport and secretion of calumenin-1/2 in living cells

Q Wang, H Feng, P Zheng, B Shen, L Chen, L Liu… - PLoS …, 2012 - journals.plos.org
Calumenin isoforms 1 and 2 (calu-1/2), encoded by the CALU gene, belong to the CREC
protein family. Calu-1/2 proteins are secreted into the extracellular space, but the secretory …

Silkworm coatomers and their role in tube expansion of posterior silkgland

Q Wang, B Shen, P Zheng, H Feng, L Chen, J Zhang… - PLoS …, 2010 - journals.plos.org
Background Coat protein complex I (COPI) vesicles, coated by seven coatomer subunits, are
mainly responsible for Golgi-to-ER transport. Silkworm posterior silkgland (PSG), a highly …

Chromatin-induced spindle assembly plays an important role in metaphase congression of silkworm holocentric chromosomes

H Mon, JM Lee, K Mita, MR Goldsmith… - Insect biochemistry and …, 2014 - Elsevier
The kinetochore plays important roles in cell cycle progression. Interactions between
chromosomes and spindle microtubules allow chromosomes to congress to the middle of …

BmCREC is an endoplasmic reticulum (ER) resident protein and required for ER/Golgi morphology

Q Wang, B Shen, P Zheng, H Feng, Y Guo… - Journal of Biological …, 2013 - ASBMB
Silkworm posterior silkgland is a model for studying intracellular trafficking. Here, using this
model, we identify several potential cargo proteins of BmKinesin-1 and focus on one …

[引用][C] Qiao Wang1, Birong Shen1, Pengli Zheng1, Hui Feng1, Yige Guo1, Wenyuan Cao1, Liang Chen1, Xiao Liu1

G Zhao, S Xu, W Shen, J Chen, J Teng - 2013 - ASBMB