Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

An effective host defense mechanism involves inflammation to eliminate pathogens from the
site of infection, followed by the resolution of inflammation and the restoration of tissue …

The transcription factor nuclear factor kappa B (NF-κB) has attracted increasing attention in
the field of cancer research from last few decades. Aberrant activation of this transcription …

Plant bioactive compounds, particularly apigenin, have therapeutic potential and functional
activities that aid in the prevention of infectious diseases in many mammalian bodies and …

Prostate cancer (PCa) is a heterogeneous disease and ranked as the second leading cause
of cancer-related deaths in males worldwide. The global burden of PCa keeps rising …

Prostate cancers that progress during androgen-deprivation therapy often overexpress the
androgen receptor (AR) and depend on AR signaling for growth. In most cases, increased …

The nuclear factor-κB (NF-κB) pathway is one of the most important cellular signal
transduction pathways involved in both physiologic processes and disease conditions. It …

Inflammation is involved in regulation of cellular events in prostate carcinogenesis through
control of the tumour micro‐environment. A variety of bone marrow‐derived cells, including …

Background New cancer therapeutic strategies must be investigated that enhance prostate
cancer treatment while minimizing associated toxicities. We have previously shown that …

The transcription factor NF-κB is a key player in inflammation, cancer development, and
progression. NF-κB stimulates cell proliferation, prevents apoptosis, and could promote …