Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Migraine can be regarded as a conserved, adaptive response that occurs in genetically
predisposed individuals with a mismatch between the brain's energy reserve and workload …

Migraine is a highly disabling neurovascular disorder characterized by a severe headache
(associated with nausea, photophobia and/or phonophobia), and trigeminovascular system …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Calcitonin gene-related peptide (CGRP) is a highly potent vasoactive peptide released from
sensory nerves, which is now proposed to have protective effects in several cardiovascular …

Introduction: Migraine is the most common of all neurological disorders. A breakthrough in
migraine treatment emerged in the early nineties with the introduction of 5-HT1B/D receptor …

Background and Objectives Anti–calcitonin gene-related peptide (CGRP)(receptor)
antibodies are approved as preventive treatment for migraine. Recent concerns have been …

Migraine is a common episodic neurovascular brain disorder associated with increased risk
of cardio-and cerebrovascular ischemia. Migraine headache is likely caused by activation of …