MicroRNAs in kidney injury and disease

N Mahtal, O Lenoir, C Tinel, D Anglicheau… - Nature Reviews …, 2022 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

TGF‐β1/Smads and miR‐21 in Renal Fibrosis and Inflammation

A Loboda, M Sobczak, A Jozkowicz… - Mediators of …, 2016 - Wiley Online Library
Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …

Epigenetics in the pathogenesis of diabetic nephropathy: Epigenetics in the pathogenesis of diabetic nephropathy

X Li, L Lu, W Hou, T Huang, X Chen… - Acta Biochimica et …, 2021 - pmc.ncbi.nlm.nih.gov
Diabetic nephropathy (DN), which is a common microvascular complication with a high
incidence in diabetic patients, greatly increases the mortality of patients. With further study …

MicroRNAs in chronic kidney disease: four candidates for clinical application

LJF Peters, J Floege, EAL Biessen… - International journal of …, 2020 - mdpi.com
There are still major challenges regarding the early diagnosis and treatment of chronic
kidney disease (CKD), which is in part due to the fact that its pathophysiology is very …

MicroRNA-21: A critical pathogenic factor of diabetic nephropathy

S Liu, W Wu, J Liao, F Tang, G Gao, J Peng… - Frontiers in …, 2022 - frontiersin.org
Diabetic nephropathy (DN), one of the most common and intractable microvascular
complications of diabetes, is the main cause of terminal renal disease globally. MicroRNA …

MicroRNA and microvascular complications of diabetes

F Barutta, S Bellini, R Mastrocola… - International journal …, 2018 - Wiley Online Library
In the last decade, miRNAs have received substantial attention as potential players of
diabetes microvascular complications, affecting the kidney, the retina, and the peripheral …

microRNAs in chronic kidney disease

H Zhao, SX Ma, YQ Shang, HQ Zhang, W Su - Clinica chimica acta, 2019 - Elsevier
Chronic kidney disease (CKD) results in high morbidity and mortality worldwide causing a
huge socioeconomic burden. MicroRNA (miRNA) exert critical regulatory functions by …

Non-coding RNAs as biomarkers and therapeutic targets for diabetic kidney disease

YY Gu, FH Lu, XR Huang, L Zhang, W Mao… - Frontiers in …, 2021 - frontiersin.org
Diabetic kidney disease (DKD) is the most common diabetic complication and is a leading
cause of end-stage kidney disease. Increasing evidence shows that DKD is regulated not …

The versatile role of MIR-21 in renal homeostasis and diseases

R Larrue, S Fellah, C Van der Hauwaert, MF Hennino… - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) are small, non-coding RNA species that control gene expression and
confer robustness to biological processes. Over the last two decades, their important roles …

MicroRNA 21 emerging role in diabetic complications: a critical update

D Roy, A Modi, M Khokhar… - Current diabetes …, 2021 - ingentaconnect.com
Background: Diabetes Mellitus is a multifactorial disease encompassing various pathogenic
pathways. To avoid morbidity and mortality related to diabetic complications, early detection …