This article provides an encompassing review of the current pipeline of putative and
developed treatments for tuberculosis, including multidrug-resistant strains. The review has …

Background Effectiveness, safety, tolerability, and adherence are critical considerations in
shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include …

With the advancements of high throughput computational screening procedures, drug
repurposing became the privileged framework for drug discovery. The structure-based drug …

Background Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis
and leads to serious complications if left untreated. Some strains of Mycobacterium …

Background There are scarce data on the clinical outcomes of persons retreated with
new/companion anti-tuberculosis (TB) drugs for multidrug-and rifampicin-resistant …

Objective To provide practical guidance on the administration of bedaquiline in children and
adolescents in the context of the treatment of multidrug-and rifampicin-resistant tuberculosis …

Operational handbook on tuberculosis. Module 4: Treatment of drug-resistant tuberculosis
treatment, is a derivative product arising from the guideline on the same topic. This …

The introduction of two novel drugs, bedaquiline and delamanid, has given hope for better
and shorter treatments of drug-resistant tuberculosis. A systematic review was conducted to …

Objective To evaluate the safety, tolerability, and efficacy of prolonged bedaquiline (Bdq)
treatment in patients with multi-drug/rifampin-resistant tuberculosis (MDR/RR-TB). Methods …

Imidazo [2, 1-b] oxazole and 2, 3-dihydroimidazo [2, 1-b] oxazole ring systems are
commonly employed in therapeutically active molecules. In this article, the authors review …