Biomedical applications of hydrogels in drug delivery system: An update
P Kesharwani, A Bisht, A Alexander, V Dave… - Journal of Drug Delivery …, 2021 - Elsevier
Conventional drug delivery system generally deals with the issues involving repeated
dosing and systemic toxicities. Since few decades, hydrogels have played a significant role …
dosing and systemic toxicities. Since few decades, hydrogels have played a significant role …
Challenges and recent progress in oral drug delivery systems for biopharmaceuticals
B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …
given route play significant roles in therapeutic efficacy and short term/long term biological …
Alginate microparticles as oral colon drug delivery device: A review
The increase in the research interest on alginate microparticles in pharmaceutical and
biomedical areas confirms its potential use as an effective matrix for drug and cell delivery …
biomedical areas confirms its potential use as an effective matrix for drug and cell delivery …
Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers
Oral delivery is the most common method for drug administration. However, poor solubility,
stability, and bioavailability of many drugs make achieving therapeutic levels via the …
stability, and bioavailability of many drugs make achieving therapeutic levels via the …
[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …
centuries, modern drug discovery and development pipelines challenge conventional …
Oral delivery of macromolecular drugs: Where we are after almost 100 years of attempts
Since the first attempt to administer insulin orally in humans more than 90 years ago, the oral
delivery of macromolecular drugs (> 1000 g/mol) has been rather disappointing. Although …
delivery of macromolecular drugs (> 1000 g/mol) has been rather disappointing. Although …
SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs
Dietary microRNAs have been shown to be absorbed by mammals and regulate host gene
expression, but the absorption mechanism remains unknown. Here, we show that SIDT1 …
expression, but the absorption mechanism remains unknown. Here, we show that SIDT1 …
Therapeutic applications of hydrogels in oral drug delivery
Introduction: Oral delivery of therapeutics, particularly protein-based pharmaceutics, is of
great interest for safe and controlled drug delivery for patients. Hydrogels offer excellent …
great interest for safe and controlled drug delivery for patients. Hydrogels offer excellent …
Characterization and biological function of milk‐derived miRNAs
R Golan‐Gerstl, Y Elbaum Shiff… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Breastfeeding is associated with reduced risk of infection, immune‐mediated
disorders, obesity, and even cancer. Recently it was found that breast milk contains a variety …
disorders, obesity, and even cancer. Recently it was found that breast milk contains a variety …
Life in 3D is never flat: 3D models to optimise drug delivery
KA Fitzgerald, M Malhotra, CM Curtin, FJ O'Brien… - Journal of controlled …, 2015 - Elsevier
The development of safe, effective and patient-acceptable drug products is an expensive
and lengthy process and the risk of failure at different stages of the development life-cycle is …
and lengthy process and the risk of failure at different stages of the development life-cycle is …