SPECT detectors: the Anger Camera and beyond

TE Peterson, LR Furenlid - Physics in Medicine & Biology, 2011 - iopscience.iop.org
The development of radiation detectors capable of delivering spatial information about
gamma-ray interactions was one of the key enabling technologies for nuclear medicine …

Maximum-likelihood methods for processing signals from gamma-ray detectors

HH Barrett, WCJ Hunter, BW Miller… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
In any gamma-ray detector, each event produces electrical signals on one or more circuit
elements. From these signals, we may wish to determine the presence of an interaction; …

Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

DigiPET: sub-millimeter spatial resolution small-animal PET imaging using thin monolithic scintillators

S España, R Marcinkowski, V Keereman… - Physics in Medicine …, 2014 - iopscience.iop.org
A new preclinical PET system based on dSiPMs, called DigiPET, is presented. The system is
based on thin monolithic scintillation crystals and exhibits superior spatial resolution at low …

[HTML][HTML] On the structure of dynamic principal component analysis used in statistical process monitoring

E Vanhatalo, M Kulahci, B Bergquist - Chemometrics and intelligent …, 2017 - Elsevier
When principal component analysis (PCA) is used for statistical process monitoring it relies
on the assumption that data are time independent. However, industrial data will often exhibit …

Maximum-likelihood estimation with a contracting-grid search algorithm

JY Hesterman, L Caucci, MA Kupinski… - IEEE transactions on …, 2010 - ieeexplore.ieee.org
A fast search algorithm capable of operating in multi-dimensional spaces is introduced. As a
sample application, we demonstrate its utility in the 2D and 3D maximum-likelihood position …

Advances in clinical molecular imaging instrumentation

BF Hutton, K Erlandsson, K Thielemans - Clinical and Translational …, 2018 - Springer
In this article, we describe recent developments in the design of both single-photon emission
computed tomography (SPECT) and positron emission tomography (PET) instrumentation …

Nonlinear least-squares modeling of 3D interaction position in a monolithic scintillator block

Z Li, M Wedrowski, P Bruyndonckx… - Physics in Medicine & …, 2010 - iopscience.iop.org
This paper presents a study of possible models to describe the relation between the
scintillation light point-of-origin and the measured photo detector pixel signals in monolithic …

A 32 mm× 32 mm× 22 mm monolithic LYSO: Ce detector with dual-sided digital photon counter readout for ultrahigh-performance TOF-PET and TOF-PET/MRI

G Borghi, BJ Peet, V Tabacchini… - Physics in Medicine & …, 2016 - iopscience.iop.org
New applications for positron emission tomography (PET) and combined PET/magnetic
resonance imaging (MRI) are currently emerging, for example in the fields of neurological …

Towards monolithic scintillator based TOF-PET systems: practical methods for detector calibration and operation

G Borghi, V Tabacchini… - Physics in Medicine & …, 2016 - iopscience.iop.org
Gamma-ray detectors based on thick monolithic scintillator crystals can achieve spatial
resolutions< 2 mm full-width-at-half-maximum (FWHM) and coincidence resolving times …