Gastric cancer: metabolic and metabolomics perspectives

S Xiao, L Zhou - International Journal of Oncology, 2017 - spandidos-publications.com
Gastric cancer is one of the most malignant tumors worldwide and remains a major health
threat in Asia-Pacific regions, while its pathological mechanism is generally unknown …

Review of mass spectrometry–based metabolomics in cancer research

DB Liesenfeld, N Habermann, RW Owen… - … , biomarkers & prevention, 2013 - AACR
Metabolomics, the systematic investigation of all metabolites present within a biologic
system, is used in biomarker development for many human diseases, including cancer. In …

Live single cell mass spectrometry reveals cancer‐specific metabolic profiles of circulating tumor cells

Y Abouleila, K Onidani, A Ali, H Shoji, T Kawai… - Cancer …, 2019 - Wiley Online Library
Recently, there has been increased attention on the analysis of circulating tumor cells (CTC
s), also known as liquid biopsy, owing to its potential benefits in cancer diagnosis and …

Identification and validation of plasma metabolomic signatures in precancerous gastric lesions that progress to cancer

S Huang, Y Guo, ZW Li, G Shui, H Tian, BW Li… - JAMA Network …, 2021 - jamanetwork.com
Importance Metabolic deregulation plays an important role in gastric cancer (GC)
development. To date, no studies have comprehensively explored the metabolomic profiles …

[HTML][HTML] A systematic review of metabolomic profiling of gastric cancer and esophageal cancer

S Huang, Y Guo, Z Li, Y Zhang, T Zhou… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Objective: Upper gastrointestinal (UGI) cancers, predominantly gastric cancer (GC) and
esophageal cancer (EC), are malignant tumor types with high morbidity and mortality rates …

1H-NMR urinary metabolomic profiling for diagnosis of gastric cancer

AW Chan, P Mercier, D Schiller, R Bailey… - British journal of …, 2016 - nature.com
Background: Metabolomics has shown promise in gastric cancer (GC) detection. This
research sought to identify whether GC has a unique urinary metabolomic profile compared …

Noninvasive diagnosis and evaluation of curative surgery for gastric cancer by using NMR-based metabolomic profiling

J Jung, Y Jung, EJ Bang, S Cho, YJ Jang… - Annals of surgical …, 2014 - Springer
Background Mass screening for gastric cancer (GC), particularly using endoscopy, may not
be the most practical approach as a result of its high cost, lack of acceptance, and poor …

Metabolite biomarker discovery for human gastric cancer using dried blood spot mass spectrometry metabolomic approach

X Wu, H Ao, H Gao, Z Zhu - Scientific Reports, 2022 - nature.com
As one of the most common malignancies, gastric cancer (GC) is the third leading cause of
cancer-related deaths in China. GC is asymptomatic in early stages, and the majority of GC …

A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine

S Gu, B Cao, R Sun, Y Tang, JL Paletta, XL Wu… - Molecular …, 2015 - pubs.rsc.org
Clinical and animal studies demonstrated that orally administered berberine had a distinct
lipid-lowering effect. However, pharmacokinetic studies showed that berberine was poorly …

[HTML][HTML] Metabolomic profiling of oesophago-gastric cancer: a systematic review

N Abbassi-Ghadi, S Kumar, J Huang, R Goldin… - European journal of …, 2013 - Elsevier
Aims This review aims to identify metabolomic biomarkers of oesophago-gastric (OG) cancer
in human biological samples, and to discuss the dominant metabolic pathways associated …