Predictive and prognostic biomarkers in colorectal cancer: A systematic review of recent advances and challenges

V Das, J Kalita, M Pal - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Colorectal cancer (CRC) is one of the leading cause of cancer deaths
worldwide. Since CRC is largely asymptomatic until alarm features develop to advanced …

[HTML][HTML] MicroRNAs potential utility in colon cancer: Early detection, prognosis, and chemosensitivity

M Hollis, K Nair, A Vyas, LS Chaturvedi… - World journal of …, 2015 - ncbi.nlm.nih.gov
Over the past decade, research has shown that aberrant expression of microRNA (miRNA)
is involved in colorectal cancer development and progression. MicroRNAs are small …

Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer

S Chell, A Kadi, AC Williams, C Paraskeva - Biochimica et Biophysica Acta …, 2006 - Elsevier
Colorectal cancer is a major cause of mortality and whilst up to 80% of sporadic colorectal
tumours are considered preventable, trends toward increasing obesity suggest the potential …

Gut microbiota manipulation as a tool for colorectal cancer management: recent advances in its use for therapeutic purposes

F Perillo, C Amoroso, F Strati, MR Giuffrè… - International Journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a multifaceted disease influenced by both environmental and
genetic factors. A large body of literature has demonstrated the role of gut microbes in …

Modulation of xenobiotic metabolising enzymes by anticarcinogens—focus on glutathione S-transferases and their role as targets of dietary chemoprevention in …

B Pool-Zobel, S Veeriah, FD Böhmer - Mutation Research/Fundamental …, 2005 - Elsevier
There is evidence that consumption of certain dietary ingredients may favourably modulate
biotransformation of carcinogens. Associated with this is the hypothesis that the risk for …

A comparative overview of general risk factors associated with the incidence of colorectal cancer

S Rasool, SA Kadla, V Rasool, BA Ganai - Tumor Biology, 2013 - Springer
Cancers found in colorectal region remain largely localized to the large intestine and rectum.
They are derived from the epithelium and are considered to be among the most frequently …

[HTML][HTML] Colorectal cancer in Saudi Arabia: The way forward

NE Elwali, O Jarrah, SG Alzahrani… - Asian Pacific journal …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer is the most common cancer in Saudi males and the second most common
cancer in Saudi females with increasing incidence throughout the last four decades …

Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

DD Nguyen, E Kim, NT Le, X Ding, RK Jaiswal… - Science …, 2023 - science.org
Despite the high lethality of colorectal cancers (CRCs), only a limited number of genetic risk
factors are identified. The mammalian ssDNA-binding protein complex CTC1-STN1-TEN1 …

DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic

B Pardini, A Naccarati, J Novotny, Z Smerhovsky… - Mutation Research …, 2008 - Elsevier
Colorectal cancer represents a complex disease where susceptibility may be influenced by
genetic polymorphisms in the DNA repair system. In the present study we investigated the …

Mapping the key technological and functional characteristics of indigenous lactic acid bacteria isolated from Greek traditional dairy products

CS Kamarinou, OS Papadopoulou, AI Doulgeraki… - Microorganisms, 2022 - mdpi.com
The aim of the current study was to isolate indigenous lactic acid bacteria (LAB) from
traditional Greek cheeses and assess their biochemical, technological, and functional …