Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

The rapid proliferation of cancer cells combined with deficient vessels cause regions of
nutrient and O2 deprivation in solid tumors. Some cancer cells can adapt to these extreme …

The authors have used an intensity modulated optical spectrometer, which measures the
phase shift across tissue experienced by intensity modulated near-infrared light, to …

Near-infrared spectroscopy (NIRS) measurements of cytochrome-c-oxidase (CCO) have the
potential to yield crucial information about cerebral metabolism at the patient bedside …

Knowledge of the nature, prognosis, and ways to treat brain lesions in neonatal infants has
increased remarkably. Neonatal hypoxic-ischaemic encephalopathy (HIE) in term infants …

Perinatal hypoxic‐ischemic encephalopathy (HIE) is an important cause of brain injury in the
newborn and can result in long‐term devastating consequences. Perinatal hypoxia is a vital …

Acute hypoxic–ischemic encephalopathy around the time of birth remains a major cause of
death and life-long disability. The key insight that led to the modern revival of studies of …

• In the literature on neonatal encephalopathy, the pervasive assumption is that once infants
with major malformations or infections have been excluded, most of the remaining cases are …

Enormous progress has been made in assessing the neonatal brain, using magnetic
resonance imaging (MRI). In this review, we will describe the use of MRI and proton …

Near-infrared (IR) light easily penetrates biological tissue, and the information offered by in
vivo spectroscopy of cerebral oxygenation is detailed and comes with a high temporal …