CRISPR/Cas12a has been believed to be powerful in molecular detection and diagnostics
due to its amplified trans-cleavage feature. However, the activating specificity and multiple …

Accurate identification of cancer cells is an essential prerequisite for cancer diagnosis and
subsequent effective curative interventions. The logic-gate-assisted cancer imaging system …

Live cell imaging is essential for obtaining spatial and temporal insights into dynamic
molecular events within heterogeneous individual cells, in situ intracellular networks, and in …

The well-developed solid-phase modified strategy at the electrode has enabled the
preparation of biosensors for the detection of multiple analytes, even in single living cells …

Accurate and sensitive strategies for Concanavalin A (Con A) sensing are conducive to the
better cognition of various important biological and physiological processes. Here, by …

To establish protein enzyme-free and simple approach for sensitive detection of single
nucleotide polymorphisms (SNPs), the nucleic acid amplification reactions were developed …

Accurate classification of tumor cells is of importance for cancer diagnosis and further
therapy. In this study, we develop multimolecular marker-activated transmembrane DNA …

To establish enzyme-free and simple approach for sensitive detection of single nucleotide
polymorphisms (SNPs), the nucleic acid amplification reactions were developed to reduce …