Advances and challenges in cell-free incorporation of unnatural amino acids into proteins
Incorporation of unnatural amino acids (UNAAs) into proteins currently is an active biological
research area for various fundamental and applied science. In this context, cell-free …
research area for various fundamental and applied science. In this context, cell-free …
Easy synthesis of complex biomolecular assemblies: wheat germ cell-free protein expression in structural biology
ML Fogeron, L Lecoq, L Cole, M Harbers… - Frontiers in Molecular …, 2021 - frontiersin.org
Cell-free protein synthesis (CFPS) systems are gaining more importance as universal tools
for basic research, applied sciences, and product development with new technologies …
for basic research, applied sciences, and product development with new technologies …
Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions
RJ Longley, MT White, E Takashima… - PLoS neglected …, 2017 - journals.plos.org
Plasmodium vivax remains an important cause of malaria in South America and the Asia-
Pacific. Naturally acquired antibody responses against multiple P. vivax proteins have been …
Pacific. Naturally acquired antibody responses against multiple P. vivax proteins have been …
Cell-free protein synthesis for producing 'difficult-to-express' proteins
X Jin, SH Hong - Biochemical Engineering Journal, 2018 - Elsevier
Biomanufacturing requires the stable production of active biological molecules including
proteins. However, a significant percentage of genes cannot be expressed efficiently in a …
proteins. However, a significant percentage of genes cannot be expressed efficiently in a …
KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization
Passive transfer studies in humans clearly demonstrated the protective role of IgG
antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is …
antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is …
[HTML][HTML] Leveraging the wheat germ cell-free protein synthesis system to accelerate malaria vaccine development
Vaccines against infectious diseases have had great successes in the history of public
health. Major breakthroughs have occurred in the development of vaccine-based …
health. Major breakthroughs have occurred in the development of vaccine-based …
Cell-free protein synthesis systems for vaccine design and production
VT Hu, NP Kamat - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•CFPS systems allow for highly optimizable and rapid protein production.•CFPS
overcomes limitations in current vaccine production and expands vaccine …
overcomes limitations in current vaccine production and expands vaccine …
Identification of novel Plasmodium vivax proteins associated with protection against clinical malaria
R Mazhari, E Takashima, RJ Longley… - Frontiers in Cellular …, 2023 - frontiersin.org
As progress towards malaria elimination continues, the challenge posed by the parasite
species Plasmodium vivax has become more evident. In many regions co-endemic for P …
species Plasmodium vivax has become more evident. In many regions co-endemic for P …
Antibody selection strategies and their impact in predicting clinical malaria based on multi-sera data
Background Nowadays, the chance of discovering the best antibody candidates for
predicting clinical malaria has notably increased due to the availability of multi-sera data …
predicting clinical malaria has notably increased due to the availability of multi-sera data …
Global Repertoire of Human Antibodies Against Plasmodium falciparum RIFINs, SURFINs, and STEVORs in a Malaria Exposed Population
Clinical immunity to malaria develops after repeated exposure to Plasmodium falciparum
parasites. Broadly reactive antibodies against parasite antigens expressed on the surface of …
parasites. Broadly reactive antibodies against parasite antigens expressed on the surface of …