Gradient scaffolds for osteochondral tissue engineering and regeneration

B Zhang, J Huang, RJ Narayan - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The tissue engineering approach for repairing osteochondral (OC) defects involves the
fabrication of a biological tissue scaffold that mimics the physiological properties of natural …

In Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone Formation

C Wittkowske, GC Reilly, D Lacroix… - … in bioengineering and …, 2016 - frontiersin.org
This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

Mechanical regulation of mesenchymal stem cell differentiation

AJ Steward, DJ Kelly - Journal of anatomy, 2015 - Wiley Online Library
Biophysical cues play a key role in directing the lineage commitment of mesenchymal stem
cells or multipotent stromal cells (MSC s), but the mechanotransductive mechanisms at play …

Accelerated orthodontic tooth movement: molecular mechanisms

H Huang, RC Williams, S Kyrkanides - American Journal of Orthodontics …, 2014 - Elsevier
Accelerating orthodontic tooth movement can significantly reduce treatment duration and
risks of side effects. The rate of orthodontic tooth movement is chiefly determined by the …

Strategies to engineer tendon/ligament-to-bone interface: biomaterials, cells and growth factors

SF Tellado, ER Balmayor, M Van Griensven - Advanced drug delivery …, 2015 - Elsevier
Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

Porous NiTi for bone implants: a review

A Bansiddhi, TD Sargeant, SI Stupp, DC Dunand - Acta biomaterialia, 2008 - Elsevier
NiTi foams are unique among biocompatible porous metals because of their high recovery
strain (due to the shape-memory or superelastic effects) and their low stiffness facilitating …

Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and …

PS Mathieu, EG Loboa - Tissue Engineering Part B: Reviews, 2012 - liebertpub.com
Mesenchymal stem cells (MSCs) hold great potential for regenerative medicine and tissue-
engineering applications. They have multipotent differentiation capabilities and have been …

The roles of exercise in bone remodeling and in prevention and treatment of osteoporosis

Y Yuan, X Chen, L Zhang, J Wu, J Guo, D Zou… - Progress in Biophysics …, 2016 - Elsevier
With a rapid increase in the aging population, osteoporosis has become a global health
problem. Although anti-resorption and anabolic drugs are available, osteoporosis cannot be …

Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery

SM Willerth, SE Sakiyama-Elbert - StemJournal, 2019 - content.iospress.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

DJ Kelly, CR Jacobs - Birth Defects Research Part C: Embryo …, 2010 - Wiley Online Library
It is becoming increasingly clear that mesenchymal stem cell (MSC) differentiation is
regulated by mechanical signals. Mechanical forces generated intrinsically within the cell in …