Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy

W Sihver, J Pietzsch, M Krause, M Baumann… - Pharmaceuticals, 2014 - mdpi.com
The epidermal growth factor receptor (EGFR) has evolved over years into a main molecular
target for the treatment of different cancer entities. In this regard, the anti-EGFR antibody …

Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues

AS Berghoff, R Bartsch, A Wöhrer, B Streubel… - Acta …, 2014 - Springer
Metastases to the central nervous system (CNS) are common in several cancer types. For
most primary tumors that commonly metastasize to the CNS, molecular biomarker analyses …

Innovative therapeutic strategies in the treatment of brain metastases

M Caffo, V Barresi, G Caruso, M Cutugno… - International Journal of …, 2013 - mdpi.com
Brain metastases (BM) are the most common intracranial tumors and their incidence is
increasing. Untreated brain metastases are associated with a poor prognosis and a poor …

Improving external beam radiotherapy by combination with internal irradiation

A Dietrich, L Koi, K Zöphel, W Sihver… - The British journal of …, 2015 - academic.oup.com
The efficacy of external beam radiotherapy (EBRT) is dose dependent, but the dose that can
be applied to solid tumour lesions is limited by the sensitivity of the surrounding tissue. The …

Targeting ErbB receptors in high-grade glioma

S Berezowska, J Schlegel - Current pharmaceutical design, 2011 - ingentaconnect.com
High-grade gliomas, including glioblastoma, are among the most malignant and treatment-
refractory human neoplasms. The tumors show high levels of resistance to conventional …

[HTML][HTML] Радионуклидная тераностика злокачественных образований

ВИ Чернов, ОД Брагина, ИГ Синилкин… - Вестник …, 2016 - cyberleninka.ru
В данном обзоре представлена основная информация, касающаяся относительно
нового перспективного направления, получившего название «тераностика» …

Resection plus whole-brain irradiation versus resection plus whole-brain irradiation plus boost for the treatment of single brain metastasis

D Rades, JD Kueter, J Gliemroth… - Strahlentherapie …, 2012 - search.proquest.com
Resection plus whole-brain irradiation versus resection plus whole-brain irradiation plus boost
for t Page 1 Strahlenther Onkol 2012 · 188:143–147 DOI 10.1007/s00066-011-0024-9 …

[HTML][HTML] Радиоиммунотерапия: современное состояние проблемы

ВИ Чернов, ОД Брагина, ИГ Синилкин… - Вопросы …, 2016 - cyberleninka.ru
В представленной работе приведены современные данные, касающиеся одного из
перспективных направлений терапии злокачественных образований, получившего …

Afatinib combined with cetuximab for lung adenocarcinoma with leptomeningeal carcinomatosis

CH Lin, MT Lin, YW Kuo, CC Ho - Lung Cancer, 2014 - Elsevier
We report a patient with non-small cell lung cancer (NSCLC) developed leptomeningeal
carcinomatosis (LMC) after 4 years of multiple treatments. High-dose tyrosine kinase …

Radionuclide teranostic of malignancies

VI Chernov, OD Bragina, IG Sinilkin… - Vestnik Rentgenologii …, 2016 - europepmc.org
This review shows some basic information regarding the relatively new and one of the
promising areas, called" theranostics' and also discusses its basic principles. Special …