While pediatric orbital tumors are most often managed in tertiary care centers, clinicians
should be aware of the signs of intraocular and orbital neoplasms. In the pediatric …

Retinoblastoma is curable when diagnosed early and treated appropriately; however, the
prognosis is dismal when the basic elements of diagnosis and treatment are lacking. In …

Human ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily and
is known to contribute to multidrug resistance (MDR) in cancer chemotherapy. Among ABC …

Background: Although the primitive haematopoietic and neuronal stem cell marker CD133 is
known to be present in cancer stem cells (CSCs) in hepatocellular carcinoma (HCC), the …

MicroRNAs and cancer stem cells have emerged as critical players in glioblastoma, one of
the deadliest human cancers. In this study, we investigated the expression and function of …

Mcm2 is a component of the DNA replication licensing complex that marks DNA replication
origins during G1 of the cell cycle for use in the subsequent S-phase. It is expressed in …

Background: Expression of ABCG2 is normally absent or low in the pancreas, but high in
human pancreatic cancer cells. The mechanism by which ABCG2 is altered in human …

Purpose Retinoblastoma (RB) is the most common intraocular tumor of early childhood. The
early onset of RB, coupled with our previous findings of cancer stem cell characteristics in …

Hypoxia is an important environmental change in many cancers. Hypoxic niches can be
occupied by cancer stem/progenitor-like cells that are associated with tumor progression …

Objective The aim of this study is to explore if ABCG2 is related to the grade of glioma and
resistance to chemotherapeutic drug for glioma. Methods The ABCG2 expression and …