Head and neck cancer was last reviewed in the Journal in 19831. At that time, there was
promising new information on a possible role for chemotherapy1, 2. During the past decade …

Background Oral cavity and oropharyngeal cancers are frequently described as part of a
group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally …

Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Purpose: The Head and Neck Intergroup conducted a phase III randomized trial to test the
benefit of adding chemotherapy to radiation in patients with unresectable squamous cell …

BACKGROUND: We designed a randomized clinical trial to test whether the addition of three
cycles of chemotherapy during standard radiation therapy would improve disease-free …

BACKGROUND The current study was conducted to characterize the risks and clinical
consequences of oral mucositis (OM) in patients with head and neck carcinoma (HNC) who …

Background. The purpose of this study was to determine the influence of weight loss on
outcome in patients with head and neck cancer undergoing concomitant chemoradiotherapy …

目的: 探索系统评价中对纳入随机对照试验(randomized controlled trial, RCT)
的评价工具(Jadad 量表和Cochrane 偏倚风险评估工具) 的应用. 方法: 以诱导化疗在头颈鳞癌 …

Oral mucositis is a common, dose limiting and potentially serious complication of both
radiation and chemotherapy. Both these therapies are non-specific, interfering with the …

Background: In 1992, we reported the first analysis of a randomized trial comparing
alternating radiotherapy and chemotherapy with radiotherapy alone in the treatment of …