Kinesins are microtubule-based motor proteins that are well known for their key roles in cell
biological processes ranging from cell division, to intracellular transport of mRNAs, proteins …

Primordial germ cells are the progenitor cells that give rise to the gametes. In some animals,
the germline is induced by zygotic transcription factors, whereas in others, primordial germ …

Fertility and gamete reserves are maintained by asymmetric divisions of the germline stem
cells to produce new stem cells or daughters that differentiate as gametes. Before entering …

Early embryogenesis relies on maternally inherited mRNAs. Although the mechanism of
maternal mRNA degradation during maternal-to-zygotic transition (MZT) has been …

INTRODUCTION The formation of the body axis in vertebrate embryos relies on the
formation of the dorsal organizer at the onset of gastrulation, which is called the Spemann …

A large amount of maternal RNA is deposited in oocytes and is reserved for later
development. Control of maternal RNA translation during oocyte maturation has been …

The proteins Oskar (Osk) in Drosophila and Bucky ball (Buc) in zebrafish act as germ plasm
organizers. Both proteins recapitulate germ plasm activities but seem to be unique to their …

Axis specification of the zebrafish embryo begins during oogenesis and relies on proper
formation of well-defined cytoplasmic domains within the oocyte. Upon fertilization …

Body axis formation in vertebrate development entails the remarkable feat of patterning a
myriad of specialized cell types and organ progenitors from a field of unpatterned …

The emergence of the bilateral embryonic body axis from a symmetrical egg has been a
long-standing question in developmental biology. Historical and modern experiments point …