Platelets and their chemokines in atherosclerosis—clinical applications

P von Hundelshausen, MMN Schmitt - Frontiers in physiology, 2014 - frontiersin.org
The concept of platelets as important players in the process of atherogenesis has become
increasingly accepted due to accumulating experimental and clinical evidence. Despite the …

Apolipoprotein E knockout models

G Kolovou, K Anagnostopoulou… - Current …, 2008 - search.proquest.com
Apolipoprotein E Knockout Models Page 1 338 Current Pharmaceutical Design, 2008, 14,
338-351 1381-6128/08 $55.00+.00 © 2008 Bentham Science Publishers Ltd. Apolipoprotein E …

Pomegranate Seed Oil as a Source of Conjugated Linolenic Acid (CLnA) Has No Effect on Atherosclerosis Development but Improves Lipid Profile and Affects the …

M Franczyk-Żarów, T Tarko, A Drahun-Misztal… - International Journal of …, 2023 - mdpi.com
The aim of this study was to evaluate the anti-atherosclerotic effect of pomegranate seed oil
as a source of conjugated linolenic acid (CLnA)(cis-9, trans-11, cis-13; punicic acid) …

Reduced Atherosclerotic Lesions in P2Y1/Apolipoprotein E Double-Knockout Mice: The Contribution of Non–Hematopoietic-Derived P2Y1 Receptors

B Hechler, M Freund, C Ravanat, S Magnenat… - Circulation, 2008 - Am Heart Assoc
Background—The P2Y1 receptor plays a key role in arterial thrombosis and is widely
expressed in many cell types involved in atherosclerosis. The aim of this study was to …

Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR−/− mice by FT-IR spectroscopy and Hierarchical Cluster Analysis

TP Wrobel, L Mateuszuk, S Chlopicki, K Malek… - Analyst, 2011 - pubs.rsc.org
Spectroscopy-based approaches can provide an insight into the biochemical composition of
a tissue sample. In the present work Fourier transform infrared (FT-IR) spectroscopy was …

Regulation and role of endoglin in cholesterol‐induced endothelial and vascular dysfunction in vivo and in vitro

M Vicen, B Vitverova, R Havelek… - The FASEB …, 2019 - Wiley Online Library
Our objective was to investigate the effect of cholesterol [hypercholesterolemia and 7‐
ketocholesterol (7K)] on endoglin (Eng) expression and regulation with respect to …

Functional alterations in endothelial NO, PGI2 and EDHF pathways in aorta in ApoE/LDLR−/− mice

G Csányi, M Gajda, M Franczyk-Zarow… - Prostaglandins & other …, 2012 - Elsevier
Adequate endothelial production of nitric oxide (NO), endothelium-derived hyperpolarizing
factor (EDHF), and prostacyclin (PGI2) is critical to the maintenance of vascular …

[PDF][PDF] Angiotensin-(1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice.

J Jawien, J Toton-Zuranska, M Gajda, A Niepsuj… - …, 2012 - academia.edu
Our interest focused on an open question whether AT-(1-7), nonpeptide receptor agonist:
AVE 0991, is able to ameliorate atherosclerosis. We used an apolipoprotein E (apoE) …

Functional effects of eggs, naturally enriched with conjugated linoleic acid, on the blood lipid profile, development of atherosclerosis and composition of …

M Franczyk-Żarów, RB Kostogrys… - British Journal of …, 2008 - cambridge.org
The objective of this study was to evaluate potential anti-atherogenic properties of hen eggs
enriched naturally with conjugated linoleic acid (CLA) isomers (cis-9, trans-11 and trans-10 …

Low carbohydrate, high protein diet promotes atherosclerosis in apolipoprotein E/low-density lipoprotein receptor double knockout mice (apoE/LDLR−/−)

RB Kostogrys, M Franczyk-Żarów, E Maślak, M Gajda… - Atherosclerosis, 2012 - Elsevier
Although in apoE/LDLR−/− mice atherosclerotic plaques develop spontaneously, various
atherogenic diets (eg Western diet) are frequently used to accelerate the disease in this …