Galangin's potential as a functional food ingredient
Foods that show positive effects on health beyond basic nutrition are called functional foods
of which familiar examples are propolis and Alpinia officinarum. Galangin (3, 4, 5 …
of which familiar examples are propolis and Alpinia officinarum. Galangin (3, 4, 5 …
Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data
Background Recently there has been an explosion of new data sources about genes,
proteins, genetic variations, chemical compounds, diseases and drugs. Integration of these …
proteins, genetic variations, chemical compounds, diseases and drugs. Integration of these …
Phytochemistry and bioactivity of Acacia sensu stricto (Fabaceae: Mimosoideae)
D Jaeger, MC O'Leary, P Weinstein, BL Møller… - Phytochemistry …, 2019 - Springer
Abstract Acacia sensu lato (Fabaceae: Mimosoideae) was recently retypified and divided
into five genera worldwide: Acacia, Acaciella, Mariosousa, Senegalia and Vachellia. Acacia …
into five genera worldwide: Acacia, Acaciella, Mariosousa, Senegalia and Vachellia. Acacia …
Learning by extrapolation from marginal to full-multivariate probability distributions: decreasingly naive Bayesian classification
Abstract Averaged n-Dependence Estimators (A n DE) is an approach to probabilistic
classification learning that learns by extrapolation from marginal to full-multivariate …
classification learning that learns by extrapolation from marginal to full-multivariate …
Identification of compounds selectively killing multidrug-resistant cancer cells
D Türk, MD Hall, BF Chu, JA Ludwig, HM Fales… - Cancer research, 2009 - AACR
There is a great need for the development of novel chemotherapeutic agents that overcome
the emergence of multidrug resistance (MDR) in cancer. We catalogued the National Cancer …
the emergence of multidrug resistance (MDR) in cancer. We catalogued the National Cancer …
Exploring gene knockout strategies to identify potential drug targets using genome-scale metabolic models
Research on new cancer drugs is performed either through gene knockout studies or
phenotypic screening of drugs in cancer cell-lines. Both of these approaches are costly and …
phenotypic screening of drugs in cancer cell-lines. Both of these approaches are costly and …
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers
Nine dihydroartemisinin acetal dimers (6–14) with diversely functionalized linker units were
synthesized and tested for in vitro antiprotozoal, anticancer and antimicrobial activity …
synthesized and tested for in vitro antiprotozoal, anticancer and antimicrobial activity …
A membrane transporter determines the spectrum of activity of a potent platinum–acridine hybrid anticancer agent
Cytotoxic drugs that are mechanistically distinct from current chemotherapies are attractive
components of personalized combination regimens for combatting aggressive forms of …
components of personalized combination regimens for combatting aggressive forms of …
Noncovalent binding to DNA: still a target in developing anticancer agents
J Portugal, F Barcelo - Current Medicinal Chemistry, 2016 - ingentaconnect.com
DNA-binding compounds are of extraordinary importance in medicine, accounting for a
substantial portion of antitumor drugs in clinical usage. However, their mechanisms of action …
substantial portion of antitumor drugs in clinical usage. However, their mechanisms of action …
Classification and virtual screening of androgen receptor antagonists
J Li, P Gramatica - Journal of chemical information and modeling, 2010 - ACS Publications
Computational tools, such as quantitative structure− activity relationship (QSAR), are highly
useful as screening support for prioritization of substances of very high concern (SVHC) …
useful as screening support for prioritization of substances of very high concern (SVHC) …