Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

Obesity is a worldwide epidemic that predisposes individuals to cardiometabolic
complications, such as type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease …

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …

Bone is a dynamic tissue that is constantly renewed by the coordinated action of two cell
types, ie., the bone-resorbing osteoclasts and the bone-forming osteoblasts. However, in …

Mesenchymal stem cells (MSC) have attracted considerable attention in the fields of cell and
gene therapy due to their intrinsic ability to differentiate into multiple lineages. The various …

Despite its rigid structure, the bone is a dynamic organ, and is highly regulated by endocrine
factors. One of the major bone regulatory hormones is vitamin D. Its renal metabolite 1α, 25 …

Human adipose tissue is a great source of autologous mesenchymal stem cells (hASCs),
which are recognized for their vast therapeutic applications. Their ability to self‐renew and …

Abstract Aims/hypothesis Thiazolidinediones (TZDs) are associated with an increased risk of
fracture but the mechanism is unclear. We sought to determine the effect of TZDs on bone …

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a widely dispersed, broad class of
synthetic chemicals with diverse biological effects, including effects on adipose and bone …

Bone formation is indirectly influenced by 1, 25-dihydroxyvitamin D3 (1, 25D3) through the
stimulation of calcium uptake in the intestine and re-absorption in the kidneys. Direct effects …