Vitiligo: a review
C Bergqvist, K Ezzedine - Dermatology, 2020 - karger.com
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of
the population worldwide. The disease is characterized by the selective loss of melanocytes …
the population worldwide. The disease is characterized by the selective loss of melanocytes …
[HTML][HTML] Janus kinase inhibitors in the treatment of vitiligo: a review
F Qi, F Liu, L Gao - Frontiers in immunology, 2021 - frontiersin.org
Vitiligo is a multifactorial reversible skin disorder characterized by distinct white patches that
result from melanocyte destruction. Activated CXCR3+ CD8+ T cells promote melanocyte …
result from melanocyte destruction. Activated CXCR3+ CD8+ T cells promote melanocyte …
[HTML][HTML] Two phase 3, randomized, controlled trials of ruxolitinib cream for vitiligo
D Rosmarin, T Passeron, AG Pandya… - … England Journal of …, 2022 - Mass Medical Soc
Background Vitiligo is a chronic autoimmune disease that causes skin depigmentation. A
cream formulation of ruxolitinib (an inhibitor of Janus kinase 1 and 2) resulted in …
cream formulation of ruxolitinib (an inhibitor of Janus kinase 1 and 2) resulted in …
Vitiligo: a focus on pathogenesis and its therapeutic implications
C Bergqvist, K Ezzedine - The Journal of dermatology, 2021 - Wiley Online Library
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …
worldwide. The characteristic white patches result from the selective loss of melanocytes …
Update on the pathogenesis of vitiligo
HZ Marchioro, CCS Castro, VM Fava… - Anais Brasileiros de …, 2022 - SciELO Brasil
Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …
Vitiligo prevalence and quality of life among adults in Europe, Japan and the USA
K Bibeau, AG Pandya, K Ezzedine… - Journal of the …, 2022 - Wiley Online Library
Background Vitiligo, an autoimmune disorder characterised by skin depigmentation, is
associated with reduced quality of life (QoL). Vitiligo may be under‐reported, in part because …
associated with reduced quality of life (QoL). Vitiligo may be under‐reported, in part because …
[HTML][HTML] SIRT3-dependent mitochondrial dynamics remodeling contributes to oxidative stress-induced melanocyte degeneration in vitiligo
X Yi, W Guo, Q Shi, Y Yang, W Zhang, X Chen… - Theranostics, 2019 - ncbi.nlm.nih.gov
Mitochondrial dysregulation has been implicated in oxidative stress-induced melanocyte
destruction in vitiligo. However, the molecular mechanism underlying this process is merely …
destruction in vitiligo. However, the molecular mechanism underlying this process is merely …
MITF and UV responses in skin: From pigmentation to addiction
NT Nguyen, DE Fisher - Pigment cell & melanoma research, 2019 - Wiley Online Library
Ultraviolet radiation (UVR) has numerous effects on skin, including DNA damage, tanning,
vitamin D synthesis, carcinogenesis, and immunomodulation. Keratinocytes containing …
vitamin D synthesis, carcinogenesis, and immunomodulation. Keratinocytes containing …
Characteristics and pathogenesis of Koebner phenomenon
X Zhang, L Lei, L Jiang, C Fu, J Huang… - Experimental …, 2023 - Wiley Online Library
The Koebner phenomenon, also known as isomorphic reaction, refers to the development of
secondary lesions with the same clinical manifestations and histopathological …
secondary lesions with the same clinical manifestations and histopathological …
[HTML][HTML] Updates and new medical treatments for vitiligo
DE Kubelis‑López… - Experimental and …, 2021 - spandidos-publications.com
Vitiligo is a multifactorial disease characterized by the loss of skin pigment, which results in
achromic macules and patches. There are currently several medical treatments available …
achromic macules and patches. There are currently several medical treatments available …