[HTML][HTML] Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels

RK Al-Ishaq, M Abotaleb, P Kubatka, K Kajo… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms

L Xu, Y Li, Y Dai, J Peng - Pharmacological research, 2018 - Elsevier
Epidemiological studies have implied that diabetes mellitus (DM) will become an epidemic
accompany with metabolic and endocrine disorders worldwide. Most of DM patients are …

Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders

B Dinda, S Dinda, S DasSharma, R Banik… - European journal of …, 2017 - Elsevier
Abstract The flavonoids, baicalin (5, 6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one-7-Od-β-
glucuronic acid) 1 and its aglycone, baicalein 2 are found in edible medicinal plants …

[HTML][HTML] Antidiabetic properties of dietary flavonoids: a cellular mechanism review

R Vinayagam, B Xu - Nutrition & metabolism, 2015 - Springer
Background Natural food products have been used for combating human diseases for
thousands of years. Naturally occurring flavonoids including flavones, flavonols, flavanones …

[HTML][HTML] Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

[HTML][HTML] An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways

Z Hu, Y Guan, W Hu, Z Xu, M Ishfaq - Iranian Journal of Basic …, 2022 - ncbi.nlm.nih.gov
The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …

Dietary flavonoids and acarbose synergistically inhibit α-glucosidase and lower postprandial blood glucose

B Zhang, X Li, W Sun, Y Xing, Z Xiu… - Journal of agricultural …, 2017 - ACS Publications
The inhibition of porcine pancreatic α-amylase and mammalian α-glucosidase by 16
individual flavonoids was determined. The IC50 values for baicalein,(+)-catechin, quercetin …

[HTML][HTML] Antihyperglycemic effect of hesperetin, a citrus flavonoid, extenuates hyperglycemia and exploring the potential role in antioxidant and antihyperlipidemic in …

R Jayaraman, S Subramani, SHS Abdullah… - Biomedicine & …, 2018 - Elsevier
Abstracts Diabetes is the major health problem in modern civilization which occurs due to
inadequate metabolism of carbohydrate and lipid could cause tremendous changes in the …

Promising influences of Scutellaria baicalensis and its two active constituents, baicalin, and baicalein, against metabolic syndrome: A review

V Baradaran Rahimi, VR Askari… - Phytotherapy …, 2021 - Wiley Online Library
Metabolic syndrome is known as a group of metabolic abnormalities with features including
central obesity, insulin resistance, hypercholesterolemia, hypertriglyceridemia, and …

Dietary plant flavonoids in prevention of obesity and diabetes

B Dinda, M Dinda, A Roy, S Dinda - Advances in protein chemistry and …, 2020 - Elsevier
Obesity and diabetes are the most prevailing chronic metabolic diseases worldwide from
mainly lipid and glucose metabolic dysfunctions and their incidence is increasing at an …